Results 141 to 150 of about 72,020 (307)

Facilitating Expedited Drug Approval—the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, EarlyView.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

Temperature‐Modulated Threshold Response in a Volatile Memristor: Toward a Biomimetic Polymodal Nociceptive System

Advanced Functional Materials, EarlyView.
This study demonstrates an artificial polymodal nociceptor whose firing threshold is actively modulated by temperature. A volatile TiN/TiOx/ZnO/TiOx/ITO memristor shows interfacial ion–driven resistive switching and membrane‐potential‐like dynamics, enabling temperature‐dependent nociceptive behavior.
Chanmin Hwang, Yuseong Jang, Myoungsu Chae, Hee‐Dong Kim   +3 more
wiley   +1 more source

Prognostic value of hemogram derived indices in polytrauma patients

Frontiers in Disaster and Emergency Medicine
IntroductionTrauma, the leading cause of mortality in young, results in significant socio-economic costs. The rate of avoidable deaths remains high mainly due to the underestimation of the initial severity of injuries.
Hela Houichi, Mohamed Kahloul, Mohamed Kahloul, Ilhem Houichi, Ilhem Houichi, Mohamed Ajmi, Mohamed Ajmi, Khalil Hochlaf, Leila Mhenni, Ines Ouahchi, Ines Ouahchi, Walid Naija, Walid Naija   +12 more
doaj   +1 more source

Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications

Advanced Functional Materials, EarlyView.
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi, Norma Mallegni, Andrea Dorigato, Mario Milazzo   +3 more
wiley   +1 more source

Avaliação da qualidade do atendimento ao traumatizado através do estudo das mortes em um hospital terciário

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Caracterizar os óbitos decorrentes de trauma em um hospital terciário e avaliar a qualidade do atendimento prestado a essas vítimas. MÉTODOS: Tratou-se de um estudo retrospectivo realizado em um centro de referência em trauma no período de um ...
Carlos Dario da Silva Costa, Sandro Scarpelini   +1 more
doaj   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Adult-Child Sexual Contact: Examining Mental Health Trainees’ Perception of the Impact on Adult Psychological-Emotional Status [PDF]

, 2018
Thirty-eight graduate students enrolled in mental health-related programs completed the Brief Symptom Inventory (BSI) indicating anticipated impact of adult-child sexual contact on the psychological status of a young adult woman from positive family ...
Ayers, Sharea, M.A., Hinze, Kristin A, M.A., L.P.C., Moore, Shavonne J., Ph.D., Petersen, Lisa P, M.A., L.P.C., Steward, Robbie J., Ph.D.   +4 more
core   +1 more source

Seta‐Inspired Mechano‐Intelligent Janus Bandage with Coordinated Adhesion–Contraction for Minimizing Scarring

Advanced Materials, EarlyView.
We developed a bioinspired mechano‐intelligent Janus bandage (MIB) with a hydrophobic flat exterior and a hydrophilic interior featuring gecko‐mimicking wedged microstructures, fabricated via micromolding and anisotropic plasma treatment. The MIB dynamically synchronizes adhesion and contraction, enabling precise force modulation.
Di Suo, Yuhe Yang, Shuai Zhao, Ho‐Pan Bei, Avery Chik‐Him Lam, Wei‐Qiang Tan, Kenneth Kak‐yuen Wong, Xin Zhao   +7 more
wiley   +1 more source

Elastomeric Micro‐Balloons for Remote Control of Cerebral Blood Flow and Real‐Time In vivo Imaging of Rodent Brain Response to Hypoperfusion

Advanced Materials, EarlyView.
This study reports the fabrication of MRI‐compatible elastomeric micro‐balloons via a multi‐step bubble casting process, where the monolithic elastomeric wall is selectively stiffened for reversible and controlled inflation and elasticity, depending on the target vessels for graded occlusion of cerebral arteries.
Jong Bin Kim, Jinghui Wang, Yinding Chi, Jingxian Wu, Alicia Ng, Guanda Qiao, Honglin Tan, Miroslaw Janowski, Piotr Walczak, Yajie Liang, Shu Yang   +10 more
wiley   +1 more source