Results 281 to 290 of about 4,217,612 (365)

Wireless In Situ Catalytic Electron Signaling‐Mediated Transcriptomic Reprogramming for Neuron Regeneration via Adaptable Antennas

open access: yesAdvanced Science, EarlyView.
A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao   +15 more
wiley   +1 more source

Dual‐Modular Hydrogel Microparticles with Precision‐Modulation of Inflammatory Microenvironment Dictate Full‐Thickness Cartilage Regeneration for Osteoarthritis Repair

open access: yesAdvanced Science, EarlyView.
Cartilage injury is a prominent pathological hallmark of osteoarthritis. In this study, we developed a two‐modular hydrogel microparticle system wherein HMP‐A effectively targets the damaged area, while HMP‐B forms an efficient connection with HMP‐A on the cartilage surface.
Xinye Chen   +5 more
wiley   +1 more source

BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration

open access: yesAdvanced Science, EarlyView.
A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou   +8 more
wiley   +1 more source

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

An Osteoconductive Janus Hydrogel with Full Barrier Protection and Adaptable Degradation Properties for Superior Bone Regeneration

open access: yesAdvanced Science, EarlyView.
The filler‐barrier hydrogel system developed by dual‐network Janus structural strategy breaks through the difficulty of a single hydrogel to combine barrier protection with bone regeneration, and realizes the regeneration‐material degradation adaptation for the field of mandibular regeneration.
Yanhui Lu   +14 more
wiley   +1 more source

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