Results 121 to 130 of about 3,286,597 (305)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Vaccine-associated Arthus reaction

Travel Medicine and Infectious Disease, 2023
Tanatorn Soravipukuntorn, MD, Anastasia Putri, MD, Kansuda Sarasaen, MSc, Phimphan Pisutsan, MD, Wasin Matsee, MD   +4 more
doaj   +1 more source

Successful reduction of urinary catheter placement for correct and incorrect indications after introduction of a prevention bundle

Antimicrobial Stewardship & Healthcare Epidemiology
The prospective before-after quality improvement study was to assess bundle effectiveness to reduce urinary catheter days and prevent associated complications.
Michela Cipriani, Matthias Schlegel, Marianne Schwark-Bähler, Samuel Henz, Philipp Kohler, Werner C. Albrich   +5 more
doaj   +1 more source

Travel Guide (Travelling Fires)

, 2009
Article in the Nov 2009 issue on fire dynamics of the magazine Fire Risk Management. Close inspection of real fires in large, open compartments reveals that they do not burn simultaneously throughout the whole compartment. Instead, these fires tend to move as flames spread, partitions or false ceilings break, and ventilation changes through glazing ...
Stern-Gottfried, Jamie, Rein, Guillermo, Torero, Jose L   +2 more
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Antimicrobial Resistance Trends, Resistance Mechanisms, and Antibiotic Consumption in COVID-19 Versus Non-COVID-19 Units: A Seven-Year Retrospective Cohort Study

Antibiotics
Background: The COVID-19 pandemic profoundly affected healthcare delivery and antibiotic prescribing, raising concerns about increasing antimicrobial resistance.
Stefan Porubcin, Alena Rovnakova, Ondrej Zahornacky, Pavol Jarcuska   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Spatiotemporal trends of HIV among international migrants: a 20-year surveillance study at Sichuan Ports, China

Frontiers in Public Health
ObjectiveTo investigate HIV epidemiological characteristics and risk factors among international migrants (including Chinese citizens departing/returning and foreign nationals entering China) at Sichuan International Travel Health Care Center (2004–2024),
Ying Shi, Qing Zhang, Lvbo Tian, Xuelong Chen, Juan Long   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source