Results 221 to 230 of about 1,125,796 (256)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Nasopharyngeal Carriage of Neisseria meningitidis in 181 Hajj and Umrah Pilgrims in Türkiye: Pre- and Post-Travel Prevalence and Serogroup Distribution n. [PDF]

Med Sci Monit
Saglan Y, Bilge U, Saglan R, Kılıc O, Dinleyici M, Balcıoglu H, Dinleyici EC.   +6 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

County-Level Geographic Access and Cardiovascular Disease Outcomes in Washington State. [PDF]

JACC Adv
Baglaev V, Dermendjian H, Dermendjian S, Mammar A, Balezi E, Hochschild AM, Pal JD.   +6 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Primary G-CSF prophylaxis in sacituzumab govitecan-treated mTNBC: real-world evidence from a multinational CEBCC-102 cohort. [PDF]

Support Care Cancer
Mirosława P, Anna PG, Aleksandra K, Małgorzata P, Justyna Ż, Miloš H, Renata S, Hana Š, Miroslava M, Agnieszka M, Karolina WS, Maja LH, Anika P, Daniel K, Jan Š, Iveta K, Iwona D, Magdalena SR, Tomasz C, Lenka R, Bogumiła CA, Aleksandra Ł, Renata PM, Michał J, Zuzana B, Marcin K.   +25 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Cluster of imported cutaneous leishmaniasis due to <i>Leishmania major</i> among travellers returning from central Tunisia, France, October 2025 to May 2026. [PDF]

Euro Surveill
Andreoletti M, Guemas E, Charpentier E, Fillaux J, Valentin A, Chauvin P, Berry A, Iriart X.   +7 more
europepmc   +1 more source

A Spatiotemporal Uncertainty-Aware Task Planning Framework for Cooperative Vehicle-UAV Remote Sensing Monitoring and Verification in Complex Terrain. [PDF]

Sensors (Basel)
Xu H, Hu L, Lu Z, Huang X, Wang Y, Chen X.   +5 more
europepmc   +1 more source