Results 121 to 130 of about 655,330 (306)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Ride-Hailing Holds Promise for Facilitating More Transit Use in the San Francisco Bay Area [PDF]

open access: yes, 2020
Increasing transit use has many benefits, including reducing traffic congestion and greenhouse gas (GHG) emissions. However, riders need to be able to get to a station in order to use transit.
Alemi, Farzad, Rodier, Caroline
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Perceptions of Bicycle-Friendly Policy Impacts on Accessibility to Transit Services: The First and Last Mile Bridge, MTI Report 12-10 [PDF]

open access: yes, 2014
The coordination of bicycle and transit modes has received close attention from public transit planners and researchers in recent years, as transit agencies around the world have installed bicycle racks on transit vehicles, implemented bicycles-on-trains
Flamm, Bradley, Rivasplata, Charles
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Guest Editorial: Debunking the Myths [PDF]

open access: yes, 2000
The modem retail travel industry has been plagued by myths created by popular media in an effort to create hype and readership, rather than report an accurate portrayal of the extraordinary health of the travel distribution system.
Clair, Keith St.
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The Importance of the Internet forTravel Agencies Operations (AStudy on TURSAB - B.Y.K. Members Travel Agencies) [PDF]

open access: yes
The Internet has a great importance on the changing business process in travel industry. This study aims at analyzing the importance, advantages, reasons and frequencies of the Internet usage in travel industry.
Ridvan Kozak
core  

Localisation of Travel Agencies in Łódź [PDF]

open access: yes, 1996
Opracowanie zawiera rezultaty badania, którego celem było poznanie lokalizacji biur turystycznych na terenie Łodzi oraz określenie i analiza czynników o niej ...
Grzelka, Dorian
core  

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