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Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Competitive Advantage Sources in Travel Agencies [PDF]
This paper aims to identify the most used ways to obtain the competitive advantage for travel agencies. Thus, following the study of the literature from the specific databases, and also following the application of a quantitative research, there were ...
Adriana Ioana Raduță
doaj
Purpose: The purpose of the article is to explore the supplier relationship practices of travel agencies in the Western Cape province. The article wants to establish the current supplier relationship practices of travel agencies in the province and to
Mornay Roberts-Lombard
doaj +1 more source
Accessible tourism: the golden key in the future for the specialized travel agencies [PDF]
Purpose – The purpose of this paper is to contribute to the comprehension of the importance of “Accessible Tourism” for the specialized travel agencies by proposing suggestions and key factors to improve the supply of accessible tourism offers.
Gamze Özogul +1 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A supply chain perspective on the supplier relationship practices of travel agencies in Gauteng
The purpose of the paper is to explore the supplier relationship practices of travel agencies in Gauteng. Gerber (2008) indicated that the current level of relationships that exists between travel agencies and their suppliers in Gauteng are fragmented ...
Mornay Roberts-Lombard
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Ethnic Specialization of Travel Agencies [PDF]
As U.S. airlines have continued to cut commissions, many travel agencies have been forced to leave the market due to excessive costs. However just as some travel agencies have closed, there has been a steady growth of new, specialized travel agencies ...
Kons \u2700, Alexander
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

