Results 41 to 50 of about 165,058 (262)
Exploring Temporal Intra-Urban Travel Patterns: An Online Car-Hailing Trajectory Data Perspective
Remote Sensing, 2021 Understanding intra-urban travel patterns is beneficial for urban planning and transportation management, among other fields. As an emerging travel mode, online car-hailing platforms provide massive and high-precision trajectory data, thus offering new ...
Chaoyang Shi +3 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Understanding cycling travel distance: The case of Medellin city (Colombia) [PDF]
Transportation Research Part D: Transport and Environment, 2020 The relevance of cycling as a mode of transportation is increasingly being recognized in many cities around the world, and the city of Medellin (Colombia) is no exception. To better understand cycling travel behavior in Medellin, we perform a multiple regression to analyze the importance of route characteristics in explaining cycling travel distance ...
Duque, J. +4 more
openaire +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Measuring long-distance travel
, 2018 Analysis of long-distance travel demand has become more relevant in recent times. The reason is the growing share of traffic induced by journeys related to remote activities, which are not part of daily life. In today’s mobile world, these journeys are responsible for almost 50 percent of the overall traffic.
Janzen, Maxim, Axhausen, Kay W.
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Journal of Mathematical and Fundamental Sciences, 2018 The investigation of landslides applying various methods has been receiving increased attention in recent years. This study was aimed at assessing the estimated distribution of landslide movement using an energy conservation formula in a lumped mass ...
Matheus Souisa +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ISPRS International Journal of Geo-InformationUnderstanding intra-urban travel patterns through quantitative analysis is crucial for effective urban planning and transportation management. In previous studies, a range of distribution functions were modeled to lay the groundwork for human mobility ...
Rui Si +3 more
doaj +1 more source