Results 51 to 60 of about 43,230 (257)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Intention to Purchase Travel Online: A SEM Analysis

open access: yesEUROPEAN RESEARCH STUDIES JOURNAL, 2019
Purpose: The study is concerned with the examination and analysis of the factors that affect an international traveler’s intention to purchase travel services online before visiting Thailand. Presently, the Kingdom is the 10th most visited country in the world.
Kornpitack, Parlakorn, Sornsaruht, Puris
openaire   +3 more sources

User-Generated Content and travel planning: An application of the Theory of Planned Behavior

open access: yesRevista Brasileira de Pesquisa em Turismo, 2012
User-Generated Content (UGC) such as online travel reviews written by travelers and posted to virtual communities are being used more frequently to communicate travel-related information.
Luiz Augusto Machado Mendes Filho   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Does travel interest mediate between motives and intention to travel? A case of young Asian travellers [PDF]

open access: yesJournal of Hospitality and Tourism Management, 2017
The rising income level of the middle class in Thailand has also raised the disposable income and interest to visit tourism destinations abroad. In last seven years the number of outbound tourists has doubled suggesting a growth rate of 15% per annum.
Mohsin, A., Lengler, J., Chaya, P.
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Analysis of the Urban Millennial Travelers’ Intention

open access: yesInternational Journal of Travel, Hospitality and Events, 2022
ABSTRACT Purpose: This study aims to identify the main factors that influence the travel intention of urban millennial travelers and why travel intentions are essential to be studied by stakeholders. Research methods: This research uses a qualitative descriptive approach, which implications travel intention from the point of view of urban ...
null Derinta Entas   +3 more
openaire   +1 more source

Home - About - Disclaimer - Privacy