Urban-Rural Disparities in Geographic Healthcare Accessibility: A Comparative Study of Nigeria and Zambia. [PDF]
Fang W +13 more
europepmc +1 more source
Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis
Objective Systemic lupus erythematosus (SLE) is a multiorgan disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith +23 more
wiley +1 more source
Differences in perceived travel distance from central versus peripheral optic flow are the same when standing and walking. [PDF]
Bansal A, Guo H, Allison RS, Harris LR.
europepmc +1 more source
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu +12 more
wiley +1 more source
Efficient engagement: opportunities for mobile methadone maintenance in geographically underserved areas. [PDF]
Bonifonte A, Garcia E, Soth S, Ngo H.
europepmc +1 more source
Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis
Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao +8 more
wiley +1 more source
Geographical accessibility of cancer hospital using geospatial technology in Bagmati province, Nepal. [PDF]
Neupane BK +5 more
europepmc +1 more source
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola +14 more
wiley +1 more source
Beyond the cruise ship: Andes hantavirus and the neglected one health dimensions of global outbreak preparedness. [PDF]
Iwu CD +4 more
europepmc +1 more source

