Results 91 to 100 of about 247,343 (260)
Le regard sur l’étranger au XIXe siècle : à propos des voyageurs français aux Baléares [PDF]
Çédille: Revista de Estudios Franceses, 2013 In the XIXth century, many French travellers visited the Balearic Islands. Their travel writing, far from being an objective reflection of the reality, conveys a gaze on the Other full of stereotypes and assumptions.
Isabelle Bes Hoghton
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
ViaticaFrançois Bernier’s work is one of the important milestones in the constitution of 17th century French orientalism. The relation of his journey, published in 1671, compiles the various letters sent to his correspondents as well as a political history of ...
Mathilde Mougin
doaj +1 more source
Traveler Writer, Romanesque Traveler: A Travel Literature Phenomenon
, 2020 The French adjective “romanesque”, which derives from the French word for “novel” and which means, in a broader sense, something out of the ordinary or something that derives from dream and imagination can be taken as a principal term to understand the situation of the traveler writer who leaves her/his home to discover beyond the limits of her/his ...
openaire +2 more sources
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Il banditismo d’onore in Corsica nell’immaginario di viaggio francese (1815-1915)
Diacronie. Studi di Storia Contemporanea, 2013 This paper aims at reconstructing the representations of Corsican banditry given by French travelers during the 19th century, taking into account travel guides and tourists reports. Between 1815 and 1915 an increasing interest in Corsica takes place; the
Giulio Tatasciore ha conseguito nel 2011 la laurea triennale in Storia contemporanea all’Università di Bologna. Nel 2012-2013 ha partecipato al «Cursus intégré franco-italien d’histoire et civilisations comparées» (Università di Bologna – Université Paris Diderot Paris VII). Attualmente sta svolgendo una tesi sull’immagine turistica del banditismo in Corsica e sul brigantaggio in Italia meridionale tra 1815 e 1915. È tra i curatori della mostra “Le relazioni italo-francesi attraverso la stampa”, organizzata nel 2013.
doaj