Results 161 to 170 of about 7,316,124 (347)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Travel and Pilgrimage Literature

open access: yes, 2018
In this chapter a variety of late antique sources – letters, travel accounts, maps, historiographical writings, vitae – are discussed regarding representations of travel and geography. Special attention is devoted to texts on religious travel to the Holy Land and the Christianizing of travel as a distinguishing feature of late antiquity.
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Value of Reliability: High Occupancy Toll Lanes, General Purpose Lanes, and Arterials [PDF]

open access: yes
In the Minneapolis-St. Paul region (Twin Cities), the Minnesota Department of Transportation (MnDOT) converted the Interstate 394 High Occupancy Vehicle (HOV) lanes to High Occupancy Toll (HOT) lanes (or MnPASS Express Lanes).
Carlos Carrion, David Levinson
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Influencer Marketing in Rural Tourism: Enhancing Destination Image and Encouraging Homestay Choices. [PDF]

open access: yesF1000Res
Chauhan R   +5 more
europepmc   +1 more source

General Introduction. Travelling Literatures

open access: yes, 2018
Contains fulltext : 190582.pdf (Publisher’s version ) (Open Access)
openaire   +1 more source

Lock-in effects of road expansion on CO2 emissions : results from a core-periphery model of Beijing [PDF]

open access: yes
In the urban planning literature, it is frequently explicitly asserted or strongly implied that ongoing urban sprawl and decentralization can lead to development patterns that are unsustainable in the long run.
Anas, Alex, Timilsina, Govinda R.
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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