Results 41 to 50 of about 13,932 (263)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Travel motivation and well-being: Analysing the mediating role of mindfulness and memorable travel experiences of Portuguese travellers

European Journal of Tourism Research
There is a common perception that tourism can directly or indirectly enhance well-being. The travellers' motivations could influence the connection between tourism and well-being.
Vivien Iacob, Saúl Neves de Jesus, Soraia Garcês, Cláudia Carmo   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Developing a multidimensional framework for wine tourist behavior: Evidence from Greece

Wine Economics and Policy, 2015
In response to the need for a better empirical understanding of the multiple factors that drive the demand of wine tourism, this paper serves a twofold objective: first, to test the distinctiveness of motivations for visiting a wine region along with a ...
Maria Alebaki, George Menexes, Alex Koutsouris   +2 more
doaj   +1 more source

Towards an interpretation of the Portuguese cultural tourist: Motivations and constraints

Tourism, 2022
The importance of cultural tourism for the development of tourist destinations has created a need for knowledge on both supply and demand sides, related to the motivations and constraints which can affect the decisions of the cultural tourist. The aim of
Ana Ramires, Anabela Monteiro, Sofia Lopes, Sara Rodrigues de Sousa, Ângela Leite   +4 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Generation Z and Travel Motivations: The Impact of Age, Gender, and Residence

Tourism and Hospitality
This study investigates the relationship between demographic factors and travel motivations among Generation Z leisure tourists through the lens of the Travel Career Pattern (TCP) theory.
Jorge Marques, Sofia Gomes, Mónica Ferreira, Marina Rebuá, Hugo Marques   +4 more
doaj   +1 more source

The moderating role of eco-destination image in the travel motivations and ecotourism intention nexus [PDF]

Journal of Tourism Futures
Purpose – This study investigates the moderating effect of eco-destination image on the relationships between travel motivations and ecotourism intention.
Nguyen Thi Khanh Chi, Hanh Pham
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source