Results 191 to 200 of about 2,772,687 (283)

Geospatial Access to Emergency Obstetric Surgery in Indonesia: Is Travel Time for Access Too Long? [PDF]

Ann Glob Health
Tjokroprawiro BA, Sulistya HA, Muharram FR, Ulhaq RA, Izza A, Prasetyo B, Novitasari K, Wiweko B, Habibie PH, Lukmana AAI, Asari MMH.   +10 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Structural and hydrodynamic controls on fluid travel time distributions across fracture networks. [PDF]

Proc Natl Acad Sci U S A
Davy P, Le Goc R, Darcel C, Pinier B, Selroos JO, Le Borgne T.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Disparity between expected spatial accessibility and actual travel time to vaccination sites: Implications for COVID-19 immunization delays. [PDF]

SSM Popul Health
Naderi H, Abbasian Z, Huang Y.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Trends in Travel Time to Obtain Surgical Care for Rural Patients.

JAMA
Mullens CL, Collins RA, Kunnath N, Probst JC, Ibrahim AM.   +4 more
europepmc   +1 more source

A lagrangian particle tracking approach of evapotranspiration partitioning to explore evaporation and transpiration travel time distributions in the root zone. [PDF]

Sci Rep
Bayat-Afshary N, Danesh-Yazdi M.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The Effects of Hospital Delivery Volume and Travel Time on Perinatal Mortality and Delivery in Transit: Causal Inference with Triangulation. [PDF]

Epidemiology
Asheim A, Nilsen SM, Opdahl S, Risnes K, Balstad Magnussen E, Carlsen F, Davies NM, Bjørngaard JH.   +7 more
europepmc   +1 more source