Results 91 to 100 of about 20,101,928 (317)

On Efficient "Time Travel" in Gödel Spacetime [PDF]

open access: yes, 2010
Here, we show that one may "time travel" in Gödel spacetime with less total acceleration than was previously known. This answers a question posed by Malament (1985, 1986, 1987)
Manchak, John Byron, John Byron Manchak
core   +1 more source

A distribution-fitting-free approach to calculating travel time reliability ratio

open access: yes, 2018
Empirical studies have revealed that travel time variability (TTV) can significantly affect travelers’ behaviors and planners’ cost-benefit assessment of transportation projects. It is therefore important to systematically quantify the value of TTV (VTTV)
Zhao-Qi Zang   +3 more
semanticscholar   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Using License Plate Recognition Data to Gain Insight into Urban Travel Time Distributions

open access: yesJournal of Highway and Transportation Research and Development
Travel time distribution is an essential tool for measuring urban traffic performance, a subject that has been studied for decades. This paper conducts a comprehensive investigation of two types of travel time distributions using extensive license plate ...
Xiaoqin Luo
doaj   +1 more source

Commuters’ valuation of travel time variability in Barcelona [PDF]

open access: yes
The value given by commuters to the variability of travel times is empirically analysed using stated preference data from Barcelona (Spain). Respondents are asked to choose between alternatives that differ in terms of cost, average travel time ...
Anna Matas, Javier Asensio
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The Development of a New Location-Based Accessibility Measure Based on GPS Data

open access: yesSensors
Accessibility is a key dimension for sustainable transport network management and planning. However, conventional location-based accessibility measures typically rely on average travel times as the sole temporal metric, neglecting detailed travel time ...
Feng Liu   +5 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Uncovering the Uncertainties and Variability of Travel Time and Fuel Consumption Using Floating Car Data: A Case Study in Wuhan

open access: yesIEEE Access
Understanding the probabilistic behavior of both travel time and fuel consumption is critical for improving urban traffic efficiency and developing reliable urban transportation systems.
Wenxin Teng   +5 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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