Results 151 to 160 of about 20,101,928 (317)

Illusion of Motion: Variation of Subjective Value of Travel Time on Freeways and Ramp Meters [PDF]

This paper explores drivers' subjective value of time under moving and stopped freeway travel conditions using a stated preference survey. Unlike previous studies that assume a constant value of time, this research relates perceived satisfaction of a ...
Feng xie, Lei Zhang, David Levinson
core  

A novel arterial travel time distribution estimation model and its application to energy/emissions estimation

Journal of Intelligent Transportation Systems / Taylor & Francis, 2018
Qichi Yang, Guoyuan Wu, K. Boriboonsomsin, M. Barth   +3 more
semanticscholar   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Leisure and the Opportunity Cost of Travel Time in Recreation Demand Analysis: A Re-Examination [PDF]

Using count data models that account for zero-truncation, overdispersion, and endogenous stratification, this paper estimates the value of access to recreational parks.
Amoako-Tuffour, Joe, Martınez-Espineira, Roberto   +1 more
core  

A Methodological Framework of Travel Time Distribution Estimation for Urban Signalized Arterial Roads

Transportation Science, 2017
F. Zheng, Henk van Zuylen, Xiao-Bo Liu
semanticscholar   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Variations in geographical accessibility: a cross-sectional nationwide study of travel times in Swedish primary care. [PDF]

BMJ Open
Isaksson D, Vengberg S, Fredriksson M.
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Mobility-informed hospital siting for accessible and lower-carbon healthcare travel: an ensemble learning study in Tianjin, China. [PDF]

Front Public Health
Zhang J, Liu F, Wang L, Yang H, Zhu R, Li C.   +5 more
europepmc   +1 more source