Results 131 to 140 of about 159,475 (252)

Patients' choice of healthcare provider for primary hip and knee arthroplasty: a national register-based observational cohort study of 62,676 patients from Norway, 2014-2018. [PDF]

Acta Orthop
Hauglann B, Kjærvik C, Stensland E, Tesfay Y, Fenstad AM, Furnes O, Ingebrigtsen T.   +6 more
europepmc   +1 more source

Versioned index data structures for time travel text search

In this work we develop a system for letting users search versioned documents – i.e.,\ncollections containing multiple versions for the same document – specifying their validity\nrange by means of time intervals. To this end, we decide to enhance the widely-used Terrier\nopen-source IR system by means of two strategies for index versioning: (i) the ...
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Timeliness of Colorectal Cancer Care in Veterans: The Role of Travel Distance. [PDF]

Cancer Rep (Hoboken)
Bradley EM, Shroder M, Edwards G, McChesney S, Kiernan C, Dittus RS, Roumie CL.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Quantifying spatial accessibility to inpatient hospices in Germany. [PDF]

BMC Health Serv Res
Petzold T, Nauck F, Banse C, Augustin J, Jaspers B, Jansky M.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Intrathecal Plasma Cell Activity as Measured by the Kappa Free Light Chain Index Is Associated With Retinal Layer Atrophy in Early Multiple Sclerosis. [PDF]

Eur J Neurol
Berek K, Schmidauer M, Föttinger F, Auer M, Berger T, Di Pauli F, Escola LV, Hofer T, Kremser B, Mangesius S, Nolte JP, Pali MC, Pemp B, Stock K, Tiefenthaler M, Walde J, Zinganell A, Deisenhammer F, Bsteh G, Hegen H.   +19 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Assessment of the healthcare burden of dengue disease in England: a retrospective analysis (2010-2023). [PDF]

J Travel Med
Kassianos G, Goodyer L, Bittencourt de Gomensoro EE, Doobaree U, Leong T, Davidson JA, Milovanović B.   +6 more
europepmc   +1 more source