Results 221 to 230 of about 15,987,795 (287)

Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC. [PDF]

Nat Med
Prelaj A, Miskovic V, Sacco M, Ferrarin A, Licciardello CM, Provenzano L, Favali M, Lerma L, Zec A, Spagnoletti A, Ganzinelli M, Lorenzini D, Guirges B, Invernizzi L, Silvestri C, Mazzeo L, Prina MM, Corrao G, Ruggirello M, Dumitrascu AD, Di Mauro RM, Monzani D, Pravettoni G, Zanitti M, Macocchi D, Marino MB, Cavalli C, Romanò R, Giani C, Armato SG, Esposito A, Bestvina CM, Spector M, Naama BR, Basheer R, Hafzadi AL, Roisman L, Watermann I, Szewczyk M, Olchers T, Richter H, Blanke-Roeser C, Siniscalchi C, Di Lello A, Arangoa T, Bartolomeo V, Spathas N, Sarris E, Fountzilas E, Roca AA, Caro-Consuegra R, Iranzo P, Fernández-Pinto M, Rodríguez-Morató J, Agnelli L, Occhipinti M, Brambilla M, Beninato T, Proto C, Kosta S, Di Palma MP, Rulli E, Steurer S, Simon R, Willis M, Pruneri G, De Braud F, Restelli M, Felip E, Peled N, Pearson AT, Linardou H, Reck M, Russo GL, Trovò F, Pedrocchi ALG, Garassino MC, I3LUNG Consortium.   +77 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

What happens next in dynamic natural scenes: Temporal discrimination is modulated by motion and scene context but not stereoscopic depth. [PDF]

J Vis
Song J, Wee G, Wolfe B.
europepmc   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Artificial Intelligence Tools in Pre-Travel Health Consultations: A Scoping Review of Clinical Evidence, Implementation Gaps, and Emerging Opportunities. [PDF]

Trop Med Infect Dis
Qasim HS, Simpson MD.
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Emergency vehicle signal priority control method for arterial intersections in an intelligent connected environment. [PDF]

Sci Rep
Cao S, Zhang X, Li W, Sun P.
europepmc   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Impact of announced wait time information on emergency department overcrowding mitigation: a simulation study. [PDF]

J Am Med Inform Assoc
Zou C, Zhang Y, Ouyang H, Sun Z.
europepmc   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source