Results 191 to 200 of about 458,798 (295)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Quantifying the carbon footprint of conference travel: the case of NMR meetings. [PDF]

Magn Reson (Gott)
Kapoor LN, Ružičková N, Živadinović P, Leitner V, Sisak MA, Mweka C, Dobbelaere J, Katsaros G, Schanda P.   +8 more
europepmc   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Socioeconomic and geographic disparities in psychiatric outcomes under Colombia's universal healthcare system. [PDF]

Psychol Med
Gerdes G, Song J, Service SK, Ramirez-Diaz AM, Diaz-Zuluaga AM, Arias A, Castaño-Ramirez M, Crossley NA, Lopez-Jaramillo C, Freimer NB, Olde Loohuis LM.   +10 more
europepmc   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Environmental impact of cataract surgery and strategies for mitigation: a life cycle assessment in an academic hospital. [PDF]

J Cataract Refract Surg
Kooistra EJ, Golsteijn L, van Bree EM, Elferink S, Brakema EA, Hermeling F, Hemelaar P, Ottenbros A, Crama N, van Zelm R, Touw HRW, Stobernack T.   +11 more
europepmc   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Assessing the financial burden on patients and their households attending hospital clinics: a pilot cross-sectional study. [PDF]

BMC Health Serv Res
Rabbitt L, Curneen J, Hobbins A, Gillespie P, Dennedy MC.   +4 more
europepmc   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Return to Activity for On- and Off-Label Cervical Arthroplasty Patients: A Multicentered Expert Panel Recommendation. [PDF]

Int J Spine Surg
Ament JD, Vokshoor A, Petros J, Zabehi T, Khachatryan A, Scott-Young M, Alex Sielatycki J, Sasso RC, Cuéllar JM, Zigler J, Guyer RD, Blumenthal S, Lanman T.   +12 more
europepmc   +1 more source