Results 161 to 170 of about 307,049 (333)

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

open access: yesAdvanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou   +9 more
wiley   +1 more source

Stability of the travelling wave in a 2D weakly nonlinear Stefan problem

open access: green, 2009
Claude-Michel Brauner   +4 more
openalex   +2 more sources

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

open access: yesAdvanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li   +13 more
wiley   +1 more source

Near‐Field Acoustic Imaging Using Fiber‐Optic Distributed Acoustic Sensing and Beamforming Techniques

open access: yesAdvanced Science, EarlyView.
This work introduces a beamforming‐based method to generate acoustic images from fiber‐optic distributed acoustic sensing (DAS) data. By performing 2D scanning around the sensing fiber, the approach enables near‐field imaging and localization of acoustic sources, even in regions distant from the fiber. A data‐driven DAS channel selection improves image
Marcelo A. Soto   +1 more
wiley   +1 more source

Plant Robotics for Sustainable and Environmentally Friendly Robots: Insights from Actuation Characteristics

open access: yesAdvanced Science, EarlyView.
Plants are promising materials for building sustainable and eco‐friendly robots due to their inherent multifunctionality, with actuation playing a crucial role. This article focuses on the physical movements of plants and, from the perspective of actuation characteristics, explores representative plant species and their behaviors, the current state of ...
Kazuya Murakami   +8 more
wiley   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Mixing of counterpropagating signals in a traveling-wave Josephson device. [PDF]

open access: yesNat Commun
Praquin M   +6 more
europepmc   +1 more source

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