Results 61 to 70 of about 66,319 (266)
European Transport Research Review, 2018 Purpose The main congestion on roads occur during peak hours, apart from incidents such as road accidents and construction works. Although there have been studies on peak period travels, these studies have only implicitly considered weekday, weekend and ...
Tina Dzigbordi Wemegah +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Un trait d’union entre la Russie et l’Europe au début du xxe siècle : le musicologue B. V. Asaf´ev
Revue des études slaves, 2013 This article explores the role of Boris Asaf´ev in the dialogue between the musical cultures of Imperial Russia, Soviet Russia and Europe during the first decades of the 20th century.
Suzanne Kassian
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Studies in 20th & 21st Century Literature, 2003 Reportedly, André Gide's Travels in the Congo (1929) had fostered reforms of the colonial policy in French Africa. In Travels , Gide reports cases of economic exploitation, abuses of power, use of terror, torture, and even homicidal raids against ...
Raphaël Lambert
doaj +1 more source
Travel to Work, Travel to Play: On Russian Tourism, Travel, and Leisure [PDF]
Slavic Review, 2003 In the introduction to this special issue, Diane P. Koenker discusses the interrelated categories of travel, tourism, and leisure, looking at contrasting definitions of the traveler and the tourist and situating Russian and Soviet experience in a broader literature. Among the themes raised in the issue's articles, she enumerates the quest for knowledge
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
HEALTH CARE FOR ADULT IMMIGRANTS AND REFUGEES: A REVIEW [PDF]
Journal of the Egyptian Society of ParasitologyAccording to human Rights Organization Amnesty International, the terms refugee, asylum seeker,and migrant are used to describe people who have left their countries and crossed borders.
HEBA AL-QURASHI
doaj +1 more source