Results 41 to 50 of about 30,862 (233)

The acute adverse health effects of kratom: an evaluation of case reports

Frontiers in Pharmacology
Mitragyna speciosa, commonly known as kratom, has gained popularity in the United States due to its stimulant and analgesic effects. Allegations of kratom-associated adverse health effects, primarily based on case reports/series, have obtained media ...
Sarah Smallets, Sydney Litvin, Grayson Abele, Sarah Kirsh, Dennis Paustenbach   +4 more
doaj   +1 more source

Multimodal Locomotion in Insect‐Inspired Microrobots: A Review of Strategies for Aerial, Surface, Aquatic, and Interfacial Motion

Advanced Robotics Research, EarlyView.
This review identifies key design considerations for insect‐inspired microrobots capable of multimodal locomotion. To draw inspiration, biological and robotic strategies for moving in air, on water surfaces, and underwater are examined, along with approaches for crossing the air–water interface.
Mija Jovchevska, Kaushik Jayaram, Nicole Xu   +2 more
wiley   +1 more source

sj-pdf-5-trc-10.1177_19400829211032585 - Supplemental material for Understanding Drivers of Unsustainable Natural Resource Use in the Comoro Islands

, 2021
Supplemental material, sj-pdf-5-trc-10.1177_19400829211032585 for Understanding Drivers of Unsustainable Natural Resource Use in the Comoro Islands by Mohamed Thani Ibouroi, Said Ali Ousseni Dhurham, Aurélien Besnard and Nicolas Lescureux in Tropical ...
Mohamed Thani Ibouroi (11284792), Nicolas Lescureux (11284798), Aurélien Besnard (556790), Said Ali Ousseni Dhurham (11284795)   +3 more
core   +1 more source

Quantitative risk assessment framework for metal exposure from tampon use

Environmental Advances
Background: Trace metals have been reported in menstrual tampons, raising concern about potential health risks. However, risk depends on bioavailable dose rather than product content, and vaginal exposure data are limited. Objectives: This study presents
Aryatara Shakya, Sarah Berlinski, Kenneth Unice, Hazel Paulo, David Falconer, Dennis Paustenbach   +5 more
doaj   +1 more source

Ferritin thresholds for cardiac and liver hemosiderosis in β-thalassemia patients: a diagnostic accuracy study

Scientific Reports, 2022
Ferritin is frequently used to screen some dire consequences of iron overload in β-thalassemia patients. The study aimed to define the best cutoff point of ferritin to screen for cardiac and liver hemosiderosis in these cases.
Hadi Darvishi-Khezri, Aily Aliasgharian, Mohammad Naderisorki, Mehrnoush Kosaryan, Mobin Ghazaiean, Hanie Fallah, Mohammad Zahedi, Hossein Karami   +7 more
doaj   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

sj-pdf-4-trc-10.1177_19400829211032585 - Supplemental material for Understanding Drivers of Unsustainable Natural Resource Use in the Comoro Islands

, 2021
Supplemental material, sj-pdf-4-trc-10.1177_19400829211032585 for Understanding Drivers of Unsustainable Natural Resource Use in the Comoro Islands by Mohamed Thani Ibouroi, Said Ali Ousseni Dhurham, Aurélien Besnard and Nicolas Lescureux in Tropical ...
Mohamed Thani Ibouroi (11284792), Nicolas Lescureux (11284798), Aurélien Besnard (556790), Said Ali Ousseni Dhurham (11284795)   +3 more
core   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

Advanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye, Wen‐jing Luo, Lu Li, Wen‐di Shuai, Ling Zhou, You‐fa Duan, Xue Chen, Jun‐kai Zhang, Wenlin Huang, Ran‐yi Liu   +9 more
wiley   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

sj-csv-2-trc-10.1177_19400829221103709 – Supplemental Material for Impacts of Dams on Freshwater Turtles: A Global Review to Identify Conservation Solutions

, 2022
Supplemental Material sj-csv-2-trc-10.1177_19400829221103709 for Impacts of Dams on Freshwater Turtles: A Global Review to Identify Conservation Solutions by Andrea Bárcenas-García, Fernanda Michalski, William H. Morgan, Rebecca K.
William H. Morgan (10739183), Rebecca K. Smith (11534478), James P. Gibbs (8026967), Andrea Bárcenas-García (12625592), Darren Norris (623285), William J. Sutherland (7488695), Fernanda Michalski (734485)   +6 more
core   +1 more source