Results 41 to 50 of about 1,956,096 (263)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Tyre Wear under Urban, Rural, and Motorway Driving Conditions at Two Locations in Spain and China
LubricantsThe recently introduced Euro 7 emissions standard regulation foresees the addition of abrasion limits for tyres sold in the European Union. The measurement procedures for tyre abrasion are described in the newly introduced Annex 10 of the United Nations (
Barouch Giechaskiel +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
EFFECT OF HYDRAULIC AND GEOMETRICAL PROPERTIES ON STEPPED CASCADE AERATION SYSTEM [PDF]
Journal of Engineering Science and Technology, 2017 Stepped cascade aeration system is commonly used to aerate the water and wastewater to increase the dissolved oxygen during pre and post treatment process.
VEDHACHALAM RATHINAKUMAR +2 more
doaj
The Influence of Wheel/Rail Contact Conditions on the Microstructure and Hardness of Railway Wheels
The Scientific World Journal, 2014 The susceptibility of railway wheels to wear and rolling contact fatigue damage is influenced by the properties of the wheel material. These are influenced by the steel composition, wheel manufacturing process, and thermal and mechanical loading during ...
Paul Molyneux-Berry +2 more
doaj +1 more source
Influence of Axle Load on the Wear of Railway Wheel Material
Modelling and Simulation in Engineering, 2023 This study investigated the influence of axle load on the wear rate of railway wheel material. Excessive wear of wheel/rail materials and reduced service life of the wheel/rail system might be caused by the increase in axle load and traffic volume.
Hewan Getachew Yenealem +2 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Applied SciencesThis study investigated the noise reduction performance of porous asphalt concrete (PAC) pavement under tire–pavement coupling conditions, addressing the limitations of field measurements and laboratory testing.
Miao Yu +7 more
doaj +1 more source