Results 131 to 140 of about 390,088 (309)

Efficacy of a Modified Treat-and-Extend Regimen of Aflibercept for Macular Oedema from Branch Retinal Vein Occlusion: 1-year prospective study outcomes

, 2019
Raw data of "Efficacy of a Modified Treat-and-Extend Regimen of Aflibercept for Macular Oedema from Branch Retinal Vein Occlusion: 1-year prospective study ...
Yusuke Arai (7025564), Hidenori Takahashi (3923933)   +1 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Comparative study on the efficacy of different aflibercept regimens in the treatment of macular edema secondary to branch retinal vein occlusion

Frontiers in Medicine
ObjectivesTo compare the efficacy of intravitreal injection of aflibercept between the treat-and-extend (TAE) and pro re nata (PRN, as needed) regimens in the treatment of macular edema secondary to branch retinal vein occlusion, to determine the best ...
Xing Du, Yuanyuan Guo, Min Du, Wen Wang, Mingkun Liu, Shanshan Li, Yanjuan Sheng   +6 more
doaj   +1 more source

Treatment patterns and visual outcomes during the maintenance phase of treat-and-extend therapy for age-related macular degeneration

, 2016
PURPOSE: To present the treatment patterns, disease activity, and visual outcomes of eyes in the maintenance phase of a treat-and-extend regimen for neovascular age-related macular degeneration (nAMD).
Morlet, Nigel, Walton, Richard, Essex, Rohan W, Young, Stephanie, Gillies, Mark C, McAllister, Ian L, Fight Retinal Blindness Study Group, Guymer, Robyn H, Arnold, Jennifer J, Nguyen, Vuong, Barthelmes, Daniel   +10 more
core   +1 more source

Changes in metamorphopsia after the treat-and-extend regimen of anti-VEGF therapy for macular edema associated with branch retinal vein occlusion.

, 2020
This study aims to investigate the changes in metamorphopsia after administering the treat-and-extend regimen of anti-vascular endothelial growth factor therapy for branch retinal vein occlusion-associated macular edema.
Shigeo Yoshida, Koh-Hei Sonoda, Keijiro Ishikawa, Kenichiro Mori, Masatoshi Haruta, Takahito Nakama, Masato Akiyama, Yoshiyuki Kobayashi, Shintaro Nakao, Iori Wada, Yuki Kubo   +10 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Challenging the Treatment Threshold: Early Faricimab Prevents Vision Loss in nAMD – A Real-World Welsh Experience

Clinical Ophthalmology
Parinita Keshav Swarnkar,1 Jaskaran Singh Bhangu,1 Christopher Stewart,2 Mohammed Rifat,1 Sarah Khalid,1 Harry Winkworth,2 Savannah Lydia Franklin-Goddard,2 Mahmoud Husseiny Awad,1 Gwyn Samuel Williams1 1Ophthalmology Department, Singleton Hospital ...
Swarnkar PK, Singh Bhangu J, Stewart C, Rifat M, Khalid S, Winkworth H, Franklin-Goddard SL, Awad MH, Williams GS   +8 more
doaj  

Comparative impact of pro re nata and treat-and-extend regimens on quality of life in patients with neovascular age-related macular degeneration

Purpose: To compare the impact of pro re nata and treat-and-extend regimens on quality of life in patients with neovascular age-related macular degeneration.
Plínio Augusto Trindade Abreu, Lais Bomediano de Souza, Osias Francisco de Souza, Juan Silva Locks Camargo, José Paulo Cabral de Vasconcelos   +4 more
core   +1 more source

"Treat and extend" dosing of intravitreal antivascular endothelial growth factor therapy for type 3 neovascularization/retinal angiomatous proliferation

, 2009
PURPOSE: The purpose of this study was to analyze long-term outcomes for the treatment of type 3 neovascularization/retinal angiomatous proliferation using a "Treat and Extend" dosing regimen for antivascular endothelial growth factor therapy.
Freund, K B, Engelbert, M, Zweifel, S A
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source