Results 181 to 190 of about 181,580 (299)

A multicenter, single-arm study using a modified faricimab treat-and-extend regimen in patients with macular edema due to central retinal vein occlusion: RVOSTAR study design protocol. [PDF]

PLoS One
Kondo M, Shimura M, Tsujikawa A, Muraoka Y, Kogo T, Akiyama Y, Hama Y, Tsujimura J, Iwasaki K, Kamei M.   +9 more
europepmc   +1 more source

Novel metrics for evaluating decision making in a 'Treat and Extend' regimen for neovascular age related macular degeneration. [PDF]

Eye (Lond), 2022
McLeish B, Morris A, Karpoor M, Babar T, Narendran N, Yang Y.   +5 more
europepmc   +1 more source

Retrospective Evaluation of Neovascular Age-related Macular Degeneration Managed With Treat-And-Extend Regimen: 5-year Results of the RENO Study

, 2018
Micaela Koci, Greggory M Gahn, P. David Freeman, Lauren Hill, Sarah A. Taylor, Aamir Aziz, Arshad M. Khanani   +6 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Aflibercept 8 mg versus Faricimab Treat-and-Extend for Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration: A Bayesian Fixed-Effect Network Meta-analysis of Clinical Trials. [PDF]

Ophthalmol Ther
Friedman SM, Xu Y, Sherman S, Kuznik A, Mojebi A, Keeping S, Chan K, Leng T, Patel N.   +8 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Aflibercept for central retinal vein occlusions: long-term outcomes of a 'Treat-and-Extend' regimen. [PDF]

BMJ Open Ophthalmol
Jaggi D, Nagamany T, Wolf S, Zinkernagel MS, Heussen FM.   +4 more
europepmc   +1 more source

Severe ocular Mpox in person living with advanced HIV treated with extended course of tecovirimat [PDF]

Lottie Brown, Pippa Sargent, Meriam Islam, C. C. Downie, Ali Hassan, Geraldine O’Hara, Sam Douthwaite, Ranjababu Kulasegaram, Scott Robbie, Emma Aarons, Iain Milligan   +10 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source