Results 1 to 10 of about 33,585,029 (332)

Tirzepatide Once Weekly for the Treatment of Obesity.

New England Journal of Medicine, 2022
BACKGROUND Obesity is a chronic disease that results in substantial global morbidity and mortality. The efficacy and safety of tirzepatide, a novel glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, in people with ...
W. Garvey, J. Frias, Ania M. Jastreboff, C. Roux, N. Sattar, D. Aizenberg, H. Mao, Shuyu Zhang, N. Ahmad, M. Bunck, I. Benabbad, Xiaotian M Zhang, Franklin H. Abalos, F. P. Manghi, C. Zaidman, Marisa L. Vico, P. Costanzo, L. Serra, I. Mackinnon, M. Hissa, M. Vidotti, J. Saraiva, B. Alves, D. Franco, Otavio Moratto, S. Murthy, Ghanshyam Goyal, Y. Yamasaki, Nobuyuki Sato, S. Inoue, Taro Asakura, M. Shestakova, E. Khaykina, E. Troshina, N. Vorokhobina, A. Ametov, S. Tu, Chwen-Yi Yang, I. Lee, Chien-Ning Huang, H. Ou, George Freeman, S. Machineni, K. Klein, Senan Sultan, A. Parsa, Juan Otero-Martinez, Alexy González, A. Bhargava, S. Brian, Carlos Ince, S. Plantholt, J. Cole, A. Lacour, D. Vega, José Deivison de Souza, Jane L. Rohlf, Roy C. St. John, Barry S. Horowitz, Hanid Audish, Rodolfo J. Galindo, Guillermo Umpiperrez, J. Ard, Brian Curtis, W. Garvey, Neil J. Fraser, J. Mandry, R. Mohseni, R. Mayfield, Talessa Powell, Carl Vance, Stephen Ong, Ana L. Lewy-Alterbaum, Alexander Murray, Amer Al-Karadsheh, Tamer G. Yacoub, K. Roberts, David L. Fried, J. Rosenstock, Bharathi Pulla, B. Bode, J. Frias, L. Klaff, R. Brazg, J. Van, Anjanette S. Tan, Toby Briskin, M. Rhee, Tira Chaicha-Brom, P. Hartley, L. Nunez, Gregorio Cortes-Maisonet, G. Soucie, S. Hsia, Thomas C. Jones   +94 more
semanticscholar   +1 more source

Remdesivir for the Treatment of Covid-19 — Final Report

New England Journal of Medicine, 2020
Background Although several therapeutic agents have been evaluated for the treatment of coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be efficacious.
J. Beigel, K. Tomashek, L. Dodd, A. Mehta, B. Zingman, A. Kalil, E. Hohmann, H. Chu, Anne F. Luetkemeyer, S. Kline, Diego López de Castilla, R. Finberg, K. Dierberg, V. Tapson, L. Hsieh, T. Patterson, R. Paredes, D. Sweeney, W. Short, G. Touloumi, D. Lye, N. Ohmagari, M. Oh, G. Ruiz-Palacios, T. Benfield, G. Fätkenheuer, M. Kortepeter, R. Atmar, C. Creech, J. Lundgren, A. Babiker, S. Pett, J. Neaton, T. Burgess, Tyler Bonnett, Michelle Green, M. Makowski, A. Osinusi, S. Nayak, H. Lane   +39 more
semanticscholar   +1 more source

Transformative Treatments [PDF]

Noûs, 2016
AbstractContemporary social‐scientific research seeks to identify specific causal mechanisms for outcomes of theoretical interest. Experiments that randomize populations to treatment and control conditions are the “gold standard” for causal inference. We identify, describe, and analyze the problem posed by transformative treatments.
Paul, L.A., Healy, Kieran
openaire   +5 more sources

Cancer treatment and survivorship statistics, 2022

Ca, 2022
The number of cancer survivors continues to increase in the United States due to the growth and aging of the population as well as advances in early detection and treatment.
K. D. Miller, Leticia M. Nogueira, Theresa P Devasia, A. Mariotto, K. R. Yabroff, A. Jemal, J. Kramer, R. Siegel   +7 more
semanticscholar   +1 more source

The improvement of Mo/4H-SiC Schottky diodes via a P2O5 surface passivation treatment [PDF]

, 2020
Molybdenum (Mo)/4H-silicon carbide (SiC) Schottky barrier diodes have been fabricated with a phosphorus pentoxide (P2O5) surface passivation treatment performed on the SiC surface prior to metallization. Compared to the untreated diodes, the P2O5-treated
Baker, G. W. C., Bonyadi, Yeganeh, Dai, Tianxiang, Dudley, M., Gammon, P. M., Han, Yan, Hindmarsh, Steven A., Li, Fan, Liu, Y., Mawby, P. A. (Philip A.), Raghothamachar, B., Renz, A. B., Shah, V. A., Sharma, Y., Vavasour, Oliver J., Walker, Marc   +15 more
core   +1 more source

Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]

, 2017
Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
core   +1 more source

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies.

BioScience Trends, 2020
The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China.
Jianjun Gao, Zhenxue Tian, Xu Yang
semanticscholar   +1 more source

User involvement and desired service developments in drug treatment: Service user and provider views [PDF]

, 2007
Aims - To investigate the existing level of user involvement at selected agencies, to examine views about user involvement from both service-user and provider perspectives and to compare desired service developments.
Beresford P, Christine Barrowclough, Department of Health, Department of Health, Department of Health, Department of Health, Hossack A, Jan Moring, National Treatment Agency, National Treatment Agency, Petra Sylvia Meier, Sabrina Schulte, Weber R   +12 more
core   +1 more source

Progressive stage transition does mean getting better: a further test of the Transtheoretical Model in recovery from alcohol problems [PDF]

, 2009
Aims To test two central assumptions of the Transtheoretical Model (TTM) regarding recovery from alcohol problems: (i) individuals making a forward transition from pre-action to action stages will show greater drinking improvements than those remaining
Babor, Beitman, Blanchard, Bonate, Callaghan, Callaghan, Callaghan, Carney, Connors, Copello, Cronbach, Davidson, Davidson, DiClemente, DiClemente, DiClemente, DiClemente, Dimitrov, Drummond, Edens, Heather, Heather, Hönekopp, McConnaughy, Miller, Miller, Miller, Miller, Prochaska, Prochaska, Project MATCH Research Group, Project MATCH Research Group, Raistrick, Rogers, Rollnick, Sutton, Sutton, Tober, UK Alcohol Treatment Trial (UKATT) Research Team, UK Alcohol Treatment Trial (UKATT) Research Team, UK Alcohol Treatment Trial (UKATT) Research Team, UK Alcohol Treatment Trial (UKATT) Research Team, Velasquez, West, Wilkinson, Willoughby   +45 more
core   +2 more sources

Estimating Dynamic Treatment Effects in Event Studies With Heterogeneous Treatment Effects [PDF]

Journal of Econometrics, 2018
Event studies are frequently used to estimate average treatment effects on the treated (ATT). In estimating the ATT, researchers commonly use fixed effects models that implicitly assume constant treatment effects across cohorts.
S. Abraham, Liyang Sun
semanticscholar   +1 more source