Results 211 to 220 of about 36,121,488 (330)

Effect of Edible Cricket Enriched Complementary Porridge and Nutrition Education on Linear Growth of Children 6-14 Months in Siaya County, Kenya: A Randomized 2 × 2 Factorial Trial. [PDF]

Matern Child Nutr
Okeyo NO, Wille CE, Kiiru SM, Sigot AJ, Ng'ang'a J, Kinyuru J, Roos N, Konyole SO.   +7 more
europepmc   +1 more source

New guidelines to evaluate the response to treatment in solid tumors

Journal of the National Cancer Institute, 2000
P. Therasse, S. Arbuck, E. Eisenhauer, J. Wanders, R. Kaplan, L. Rubinstein, J. Verweij, M. Glabbeke, A. T. Oosterom, M. Christian, S. Gwyther   +10 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Treatment resistance in first-episode psychosis. [PDF]

World Psychiatry
McCutcheon RA, McGuire P, Upthegrove R, Pillinger T.   +3 more
europepmc   +1 more source

The role of different stigma perceptions in treatment seeking and dropout among active duty military personnel.

, 2015
Thomas W. Britt, Kristen S. Jennings, Janelle H. Cheung, Cynthia L. S. Pury, Heidi M. Zinzow   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

A data re-analysis confirms the value of symptom networks in predicting psychotherapy outcome. [PDF]

World Psychiatry
Schumacher L, Kriston L, Ebrahimi OV, Finnemann A, Klein JP, Haslbeck JMB.   +5 more
europepmc   +1 more source

Mechanisms and Treatment of Late-Life Depression

, 2021
George S. Alexopoulos
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Pharmacologic Treatment of Kleine-Levin Syndrome: A Case Report and Comprehensive Review of Therapeutic Options. [PDF]

Neuropsychopharmacol Rep
Thawongit S, Siripornpanich V, Thampratankul L.   +2 more
europepmc   +1 more source