Results 281 to 290 of about 33,585,029 (332)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

Ribitol treatment rescues dystroglycanopathy mice with common L276I mutation. [PDF]

PLoS One
Wu B, Lu PJ, Drains M, Shah S, Blaeser A, Leroy V, Killilee J, Holbrook M, Lu QL.   +8 more
europepmc   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Isolating Brain Mechanisms of Expectancy Effects on Pain: Cue-Based Stimulus Expectancies versus Placebo-Based Treatment Expectancies. [PDF]

J Neurosci
Necka EA, Akintola T, Yu Q, Amir CM, Oretsky O, Atlas LY.   +5 more
europepmc   +1 more source

Evaluation of the efficacy of FDG-PET/CT in assessing the effects of BMMSC treatment in aged rhesus monkeys. [PDF]

Stem Cell Res Ther
Zhang Y, Li J, Lü L, Li Y, Yang Z, Yang S, Zhu X, He R, Pan X, Zhu G.   +9 more
europepmc   +1 more source

Programmed death 1 inhibitor combined with radiotherapy decreases epidermal growth factor receptor expression in breast cancer. [PDF]

Hereditas
Wu Y.
europepmc   +1 more source

Evaluation of the efficacy of clear aligners in mandibular advancement and their effect on mandibular trabecular structures using fractal dimension analysis. [PDF]

BMC Oral Health
Karslı N, Gonca M, Türksever GM, Beyaz NA.   +3 more
europepmc   +1 more source

Real-World Effectiveness of Rebamipide on Gastritis Symptoms: A Patient-Focused Approach. [PDF]

Clin Transl Sci
Woo HJ, Kwon TK, Moon SJ, Kim MG.
europepmc   +1 more source