Results 91 to 100 of about 172,855 (261)

Interventions for enhancing medication compliance/adherence with benefits in treatment outcomes.

GMS health technology assessment, 2011
Poor compliance or adherence in drug therapy can cause increased morbidity, mortality and enormous costs in the healthcare system (in Germany annually approximately 10 billion euros). Different methods are used for enhancing the compliance or adherence.The evaluation addresses the questions about existence, efficacy, cost-benefit relation as well as ...
Vitali, Gorenoi, Matthias P, Schönermark, Anja, Hagen   +2 more
openaire   +1 more source

Meniscus‐Guided Soft‐Lithographic Assembly of Grid‐Type Molecular Martensite Films for Single‐Crystal‐Like Actuation

Advanced Functional Materials, EarlyView.
A meniscus‐guided microtransfer molding strategy enables scalable fabrication of grid‐type molecular martensite films with b‐axis‐correlated preferential texture. Sequential growth across microchannel intersections creates structurally continuous grids and robust thermoelastic actuation (∼11% strain, > 50 cycles, maximum force density: 7.1 × 109 N m−3).
Sooyeon Ra, Sourabh R. Jagdale, Jin Hyeok Jang, Minwoo Jang, Kyoungtae Hwang, Taewoo Lee, Eun Hui Jeong, Soon Ho Yoon, Byung Joon Moon, Jangyup Son, Dong‐Su Lee, Sukang Bae, Jun Dong Park, Tae‐Wook Kim, Sangmin An, Sang Kyu Park   +15 more
wiley   +1 more source

Adherence and Compliance with Endocrine Treatment After Primary Breast Cancer Treatment: A Cross-Sectional Qualitative Study

Medicina
Introduction Breast cancer is the most common cancer in women, with 80% being oestrogen receptor positive, requiring endocrine treatment to reduce recurrence. Treatment compliance is vital; however, 10-50% of patients take an incorrect dosage or discontinue therapy. This has shown a 20% mortality increase. Additionally, endocrine therapy has been said
Odhran Cosgrove, Sadaf Zehra, Dinesh Kumar Thekkinkattil   +2 more
openaire   +3 more sources

Adherence Maintenance Framework in Health Psychology: Promoting HIV Treatment Compliance in Kenya

, 2012
Adherence to antiretroviral therapy (ART) is critical for managing HIV in resource-limited settings such as Kenya, where access and affordability of healthcare services are significant challenges. The approach is primarily conceptual, drawing from existing literature in health psychology and psychosocial interventions.
Wamunyanki, Wambugu, Odinga, Oginga
openaire   +2 more sources

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Effects of adherence to treatment for repositioning therapy, physical therapy, and cranial remolding orthoses in infants with cranial deformation

Journal of Rehabilitation and Assistive Technologies Engineering
Deformational head shapes are most often treated through repositioning therapy (RT) and/or cranial remolding orthotic (CRO) treatment. However, there is conflicting evidence about the effectiveness of each method, and treatment compliance is suspected to
Victoria Moses, Caitlin Deville, Susan Simpkins, Jijia Wang, Tally Marlow, Cayman Holley, Shea Briggs, Olivia Sheffer, Amy Payne, Lindsay Pauline, Tristine Lam, Ashton Blasingim, Tiffany Graham   +12 more
doaj   +1 more source

Sodium Alginate‐Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection

Advanced Healthcare Materials, EarlyView.
A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood, Venkata S. Akshintala, Surya T. Evani, Rebecca A. Krimins, Yihan Wang, Keith Freel, Ahmed Ibrahim, Saowanee Ngamruengphong, Mouen Khashab, Stephen W. Hoag   +9 more
wiley   +1 more source