The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao +8 more
wiley +1 more source
Optimising Management of Paediatric Distal Radius Torus Fractures: A Complete Two-Cycle Audit Assessing Compliance With National Institute for Health and Care Excellence (NICE) Guideline NG38. [PDF]
Rajan P +5 more
europepmc +1 more source
Thermally activated LiHCOO induces in situ pseudo‐halide diffusion, promoting buried interface strain release and perovskite crystallization. The monoclinic LiHCOO phase forms an open framework structure that enhances HCOO− diffusion and drives interfacial restructuring.
Chao Gao +4 more
wiley +1 more source
Analysis of key obstacles affecting long-term inhalation therapy compliance in children with bronchial asthma at primary hospitals. [PDF]
Fan D, Wu Y, Shi W.
europepmc +1 more source
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou +4 more
wiley +1 more source
Optimizing the invisible costs of anti-VEGF: The road to regularity. [PDF]
Agrawal S.
europepmc +1 more source
Compliance of procalcitonin-guided antibiotic therapy in adult infectious patients in China: a multicenter real-world retrospective study. [PDF]
Li X +5 more
europepmc +1 more source
Comment on: Final results from the vedolizumab extended access program multinational study demonstrate long-term treatment persistence and safety. [PDF]
Borrás-Blasco J +2 more
europepmc +1 more source
Impact of socioeconomic status on tumor stage, molecular subtype distribution, treatment adherence, and survival outcomes in breast cancer. [PDF]
Li T, Liu H, Ma S, Guo L, Li J.
europepmc +1 more source
Quality of antibiotics prescription in hospitals in Burkina Faso: a multispecialty clinical audit. [PDF]
Diallo D +10 more
europepmc +1 more source

