Results 251 to 260 of about 5,745,068 (294)

Semaglutide in obesity and type 2 diabetes: A review of clinical trial evidence from 1 to 5 semaglutide treatment effect in people with obesity program.

Indian J Pharmacol
Khanna A, Kumar V, Gola S.
europepmc   +1 more source

Testing for a treatment effect in a selected subgroup. [PDF]

Stat Methods Med Res
Stallard N.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Permutation tests for detecting treatment effect heterogeneity in cluster randomized trials. [PDF]

Stat Methods Med Res
Maleyeff L, Li F, Haneuse S, Wang R.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Variations in quantifying patient reported outcome measures to estimate treatment effect. [PDF]

World J Methodol
Muthu S, Vadranapu S.
europepmc   +1 more source

The predictive value of combined detection of serum IL-33, TSLP and eosinophils in the treatment effect and exacerbation risk of chronic obstructive pulmonary disease. [PDF]

BMC Pulm Med
Xu J, Wang Y, Gu H, Chen X.
europepmc   +1 more source

Chemo-Nonresponsive Telangiectatic Osteosarcoma With Oligometastatic Recurrence Managed With Multimodality Therapy Including Stereotactic Ablative Body Radiotherapy (SABR): A Case Report With a Pathologic Treatment Effect. [PDF]

Cureus
Orr WS, Vijayakumar S, Al Hmada Y, Mobit P, Collier AB, Barr J, De Delva PE, Davis DB, Yang CC, Nittala R.   +9 more
europepmc   +1 more source

Supportive Evidence of Surrogate End Points Based on Treatment Effect of Corticosteroid in IgA Nephropathy. [PDF]

Kidney Int Rep
Sasaki T, Tsuboi N, Koike K, Ueda H, Okabe M, Yokote S, Shimizu A, Hirano K, Kawamura T, Yokoo T, Suzuki Y, J-IGACS Working Group.   +11 more
europepmc   +1 more source

Estimating Treatment Effect Heterogeneity in Psychiatry: A Review and Tutorial With Causal Forests. [PDF]

Int J Methods Psychiatr Res
Sverdrup E, Petukhova M, Wager S.
europepmc   +1 more source