Results 41 to 50 of about 28,962,370 (286)

Bounds on Treatment Effects on Transitions [PDF]

SSRN Electronic Journal, 2016
40 pages, 5 ...
Geert Ridder, Johan Vikström, Martin Weidner   +2 more
openaire   +7 more sources

Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials.

The Lancet Diabetes and Endocrinology, 2019
BACKGROUND Change in albuminuria has strong biological plausibility as a surrogate endpoint for progression of chronic kidney disease, but empirical evidence to support its validity is lacking.
H. Heerspink, T. Greene, H. Tighiouart, R. Gansevoort, J. Coresh, Andrew L. Simon, T. Chan, F. Hou, J. Lewis, F. Locatelli, M. Praga, F. Schena, A. Levey, Lesley A. Inker   +13 more
semanticscholar   +1 more source

Double/Debiased/Neyman Machine Learning of Treatment Effects [PDF]

, 2017
Chernozhukov et al. (2016) provide a generic double/de-biased machine learning (ML) approach for obtaining valid inferential statements about focal parameters, using Neyman-orthogonal scores and cross-fitting, in settings where nuisance parameters are ...
V. Chernozhukov, D. Chetverikov, Mert Demirer, E. Duflo, Christian Hansen, W. Newey   +5 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Treatment Effect Performance of the X-Learner in the Presence of Confounding and Non-Linearity

Mathematical and Computational Applications, 2023
This study critically evaluates a recent machine learning method called the X-Learner, that aims to estimate treatment effects by predicting counterfactual quantities.
Bevan I. Smith, Charles Chimedza, Jacoba H. Bührmann   +2 more
doaj   +1 more source

GFR Slope as a Surrogate End Point for Kidney Disease Progression in Clinical Trials: A Meta-Analysis of Treatment Effects of Randomized Controlled Trials.

Journal of the American Society of Nephrology, 2019
BACKGROUND Surrogate end points are needed to assess whether treatments are effective in the early stages of CKD. GFR decline leads to kidney failure, but regulators have not approved using differences in the change in GFR from the beginning to the end ...
Lesley A. Inker, H. Heerspink, H. Tighiouart, A. Levey, J. Coresh, R. Gansevoort, Andrew L. Simon, Jian Ying, G. Beck, C. Wanner, J. Floege, P. Li, V. Perkovic, E. Vonesh, T. Greene   +14 more
semanticscholar   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Colorectal cancer mortality in persons with severe mental illness: a scoping review with meta-analyses of observational studies

Acta Oncologica
Background and purpose: Persons with severe mental illnesses (SMIs) have reduced participation in colorectal cancer (CRC) screening programs, higher odds of advanced stage at diagnosis, and are less likely to receive adequate treatment than the general ...
Paula R. Pop, Gitte S. Larsen, Mette K. Thomsen, Christoffer Johansen, Robert Zachariae, Bolette Skjødt Rafn   +5 more
doaj   +1 more source

THE RIGHT TO EFFECTIVE BEHAVIORAL TREATMENT [PDF]

Journal of Applied Behavior Analysis, 1988
We propose that individuals who are recipients or potential recipients of treatment designed to change their behavior have the right to a therapeutic environment, services whose overriding goal is personal welfare, treatment by a competent behavior analyst, programs that teach functional skills, behavioral assessment and ongoing evaluation, and the ...
R, Van Houten, S, Axelrod, J S, Bailey, J E, Favell, R M, Foxx, B A, Iwata, O I, Lovaas   +6 more
openaire   +4 more sources

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source