Results 191 to 200 of about 31,464 (260)

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor   +4 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

Delivering the future of immunotherapy: A state-of-the-art review of gene editing in immune cells with lipid nanoparticles. [PDF]

open access: yesMater Today Bio
Ciganek I   +6 more
europepmc   +1 more source

Artificial Intelligence Resources for the Screening of Titles and Abstracts in Systematic Reviews: A Scoping Review

open access: yesCochrane Evidence Synthesis and Methods, Volume 4, Issue 5, September 2026.
ABSTRACT Introduction Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem‐solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study ...
Ana M. Barragán   +5 more
wiley   +1 more source

Mechanisms and Predisposing Conditions for Statin‐Induced New‐Onset Type 2 Diabetes Mellitus: A Paradox Relative to Their Pleiotropic Metabolic Effects

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
The primary function of statins is to inhibit cholesterol synthesis, which contributes to their antidiabetic effects. However, the majority of the diabetic effects of statins are due to inhibition of isoprenoid synthesis. Atorvastatin, simvastatin and rosuvastatin possess the most pronounced diabetogenic properties. In contrast, lovastatin, fluvastatin,
Ali Nosrati Andevari, Mohsen Koolivand
wiley   +1 more source

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 3, Page 277-289, September 2026.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He   +11 more
wiley   +1 more source

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