Results 41 to 50 of about 17,612,218 (346)

Data collection methods for patient-reported outcome measures in cancer randomised controlled trials: a protocol for a rapid scoping review

BMJ Open
Background There are different modes and ways to assess patient-reported outcomes (PROs) in clinical trials. However, there is little systematic information on how often different modes of assessment (MOA) are used in cancer clinical trials and how ...
Deborah Fitzsimmons, Bernhard Holzner, Johannes M Giesinger, Jens Lehmann, Daniela Krepper, Madeline Pe, Dagmara Kuliś, Monika Sztankay, Scottie Kern   +8 more
doaj   +1 more source

An Epidemiologic and Clinical Study of Snake Bites during a Five-Year Period in Karoon, Iran [PDF]

Asia Pacific Journal of Medical Toxicology, 2018
Background:Snakebite is one of the most common health problems in endemic regions such as Iran. Due to the potential life-threatening impact of snake envenomation and biodiversity of snakes, it seems that epidemiological studies are required, as the ...
Ghazal Hafezi, Ali Hasan Rahmani, Mohammad Soleymani, Pedram Nazari   +3 more
doaj   +1 more source

Remdesivir for the Treatment of Covid-19 — Final Report

New England Journal of Medicine, 2020
Background Although several therapeutic agents have been evaluated for the treatment of coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be efficacious.
J. Beigel, K. Tomashek, L. Dodd, A. Mehta, B. Zingman, A. Kalil, E. Hohmann, H. Chu, Anne F. Luetkemeyer, S. Kline, Diego López de Castilla, R. Finberg, K. Dierberg, V. Tapson, L. Hsieh, T. Patterson, R. Paredes, D. Sweeney, W. Short, G. Touloumi, D. Lye, N. Ohmagari, M. Oh, G. Ruiz-Palacios, T. Benfield, G. Fätkenheuer, M. Kortepeter, R. Atmar, C. Creech, J. Lundgren, A. Babiker, S. Pett, J. Neaton, T. Burgess, Tyler Bonnett, Michelle Green, M. Makowski, A. Osinusi, S. Nayak, H. Lane   +39 more
semanticscholar   +1 more source

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

Population Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

Between Droughts and Floods: The Seasonal Response of Freshwater Snails in Artificial Reservoirs in the Brazilian Semiarid Region

Population Ecology, EarlyView.
We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva, João Hemerson de Sousa, Adriana Josefa da Rocha, Manuella Feitosa Leal, Lucas Ariel de Sousa Aguiar, Tamaris Gimenez Pinheiro, Edson Lourenço da Silva   +6 more
wiley   +1 more source

Diabetes in tuberculosis patients: An emerging public health concern and the determinants and impact on treatment outcome

Journal of Family and Community Medicine, 2020
BACKGROUND: Tuberculosis (TB) and diabetes mellitus are still of much public health concern. Screening of TB patients for diabetes will ensure early case detection, better management of diabetes, and better TB treatment outcome.
Sembagamuthu Sembiah, Vivek Nagar, Devendra Gour, Dinesh K Pal, Arun Mitra, Jayeeta Burman   +5 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Time to develop aspiration pneumonia and its predictors among stroke patients admitted at specialized hospitals in Western Amhara during the armed conflict period, 2024

Scientific Reports
Stroke, characterized by a sudden neurologic deficit due to reduced cerebral perfusion, often leads to complications such as aspiration pneumonia. This acute lung infection occurs when substances from the gastrointestinal tract, including endogenous ...
Addisu Getie, Etsubdink Dessalew, Aster Tadesse, Mihretie Gedfew, Baye Tsegaye Amlak, Tadesse Yirga Akalu   +5 more
doaj   +1 more source

Factors Associated With Discharge Destination in Advanced Cancer Patients With Bone Metastasis in a Japanese Hospital [PDF]

Annals of Rehabilitation Medicine, 2018
Objective To analyze patient characteristics of cancer rehabilitation and outcomes at our hospital. Methods This retrospective study analyzed 580 patients, who underwent cancer rehabilitation at our hospital and rehabilitation outcome after therapy were ...
Katsuhiro Hayashi, Tetsutaro Yahata, Ryota Muramoto, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hisaki Aiba, Yoshihiro Araki, Hiroyuki Tsuchiya   +11 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source