Results 41 to 50 of about 5,119,981 (327)

Residual Weighted Learning for Estimating Individualized Treatment Rules

open access: yes, 2015
Personalized medicine has received increasing attention among statisticians, computer scientists, and clinical practitioners. A major component of personalized medicine is the estimation of individualized treatment rules (ITRs).
Khan, Umer   +3 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Treatment outcomes and associated factors of stroke in Ethiopia: a systematic review and meta-analysis

open access: yesBMC Cardiovascular Disorders
Introduction Stroke is characterized by a sudden onset of focal or global neurological deficits resulting from reduced cerebral blood flow. Poor treatment outcomes are primarily caused by uncontrolled blood pressure and delayed hospital arrival.
Addisu Getie   +2 more
doaj   +1 more source

Semiparametric Causal Sufficient Dimension Reduction Of High Dimensional Treatments

open access: yes, 2020
Cause-effect relationships are typically evaluated by comparing the outcome responses to binary treatment values, representing two arms of a hypothetical randomized controlled trial. However, in certain applications, treatments of interest are continuous
McNutt, Todd   +2 more
core  

Identification region of the potential outcome distributions under instrument independence [PDF]

open access: yes, 2009
This paper examines identification power of the instrument exogeneity assumption in the treatment effect model. We derive the identification region: The set of potential outcome distributions that are compatible with data and the model restriction.
Kitagawa, T.
core  

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

A comparable study of clinical and optical outcomes after 1.8, 2.0 mm microcoaxial and 3.0 mm coaxial cataract surgery [PDF]

open access: yesInternational Journal of Ophthalmology, 2016
AIM: To evaluate the clinical and optical outcomes after clear corneal incision cataract surgery (CICS) with three different incision sizes (1.8, 2.0 and 3.0 mm).
Yi-Bo Yu   +5 more
doaj   +1 more source

A Statistical Model for Stroke Outcome Prediction and Treatment Planning

open access: yes, 2016
Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit   +3 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Treatment and Outcome of Ankle Fractures at the Moi Teaching and Referral Hospital

open access: yesThe Annals of African Surgery, 2014
Background: Ankle fractures are common and protocols for their management are generally well established. Despite this, a significant proportion of the patients get unfavourable outcomes after being managed for this injury.
Kilonzo N   +4 more
doaj  

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