Results 111 to 120 of about 10,762,797 (269)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Conservation Priority Index (CPI).

open access: yes, 2015
Conservation Priority Index (CPI).
Matthew Merrifield (773953)   +5 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

National Treatment Purchase Fund annual report 2004.

open access: yes, 2004
The mission of the National Treatment Purchase Fund is to reduce the length of time public patients are on hospital waiting lists by offering them a choice in obtaining access to treatment quickly, safely and to a high standard of patient satisfaction ...
National Treatment Purchase Fund
core  

Index 1985 [PDF]

open access: yes, 1985
This is the 1985 edition of the Index. The Index is written by student editors, and it is the college’s yearbook. It includes an annual record of events at Wooster. This specific Index is divided into different sections including college life, activities,
Editors, Index, Index Editors,
core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Necesidad de tratamiento ortodóncico. Politécnico “Antonio Guiteras”. Plaza. 2012

open access: yesRevista Habanera de Ciencias Médicas, 2014
Introducción: las maloclusiones provocan trastornos físicos, funcionales y psicosociales, especialmente en niños y adolescentes. Objetivo: describir la severidad y necesidad de tratamiento ortodóncico en escolares del politécnico “Antonio Guiteras ...
Mai Hoang Anh   +3 more
doaj  

Universal Health Coverage and Health Equity in West Africa: Tracking Progress Toward SDG 3.8 in Ghana and Liberia

open access: yesPublic Health Challenges
Background Achieving universal health coverage (UHC) remains a key priority for many low‐ and middle‐income countries, yet equity in access continues to be a significant challenge. This study examines the level and distribution of health service coverage
Samuel Asamoah   +7 more
doaj   +1 more source

National Treatment Purchase Fund annual report 2004

open access: yes, 2005
2004 has been a busy and successful year for the National Treatment Purchase Fund (NTPF)The NTPF is one of the initiatives outlined in the Health Strategy and Programme for Government and was set up in April 2002.
National Treatment Purchase Fund
core  

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