Results 121 to 130 of about 14,958,381 (308)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An observational treatment study of metacognition in anxious-depression. [PDF]

Elife, 2023
Fox CA, Lee CT, Hanlon AK, Seow TXF, Lynch K, Harty S, Richards D, Palacios J, O'Keane V, Stephan KE, Gillan CM.   +10 more
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Association between virtual visits and health outcomes of people living with HIV: A cross-sectional study.

PLoS ONE
BackgroundVirtual care has been integrated as a modality of care in Ontario, yet its effectiveness for people living with HIV remains largely unexplored.ObjectivesWe aimed to determine the association of visit modality (virtual, in-person, or both) on ...
Nadia Rehman, Lawrence Mbuagbaw, Dominik Mertz, Giulia M Muraca, Aaron Jones, Ontario HIV Treatment Network Cohort Study   +5 more
doaj   +1 more source

Ocular Hypertension Treatment Study [PDF]

Archives of Ophthalmology, 2009
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Socioeconomic determinants of virtual care use among people living with HIV in a clinical cohort in Ontario, Canada: A cross-sectional study.

PLoS ONE
BackgroundRetention in HIV care is essential for achieving optimal health outcomes and extending life expectancy among people living with HIV. However, socioeconomic challenges frequently hinder consistent engagement in care.
Nadia Rehman, Lawrence Mbuagbaw, Dominik Mertz, Giulia M Muraca, Aaron Jones, Ontario HIV Treatment Network Cohort Study   +5 more
doaj   +1 more source

Clinical Validation of a Machine Learning-Based Biomarker Signature to Predict Response to Cytotoxic Chemotherapy Alone or Combined with Targeted Therapy in Metastatic Colorectal Cancer Patients: A Study Protocol and Review

Life
Metastatic colorectal cancer (mCRC) is a severe condition with high rates of illness and death. Current treatments are limited and not always effective because the cancer responds differently to drugs in different patients.
Duilio Pagano, Vincenza Barresi, Alessandro Tropea, Antonio Galvano, Viviana Bazan, Adele Caldarella, Cristina Sani, Gianpaolo Pompeo, Valentina Russo, Rosa Liotta, Chiara Scuderi, Simona Mercorillo, Floriana Barbera, Noemi Di Lorenzo, Agita Jukna, Valentina Carradori, Monica Rizzo, Salvatore Gruttadauria, Marco Peluso   +18 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Responses of Diabetes Mellitus Patients Who Used Complementary Medicine [PDF]

, 2016
Diabetes Mellitus as a chronic disease tend to seek appropriate medical treatment to heal the condition. Health-seek searched can be either medical treatment or Complementary and Alternative Medicine.
Agil, M. (Mangestuti), Joeliantina, A. (Anita), Jonosewojo, A. (Arijanto), Kusnanto, K. (Kusnanto), Qomaruddin, M. B. (M)   +4 more
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