Results 201 to 210 of about 14,986,124 (359)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Prevalence of ADHD in a Sample of Heroin Addicts Receiving Agonist Treatment-Study Conducted in a Public Addiction Service. [PDF]

Int J Environ Res Public Health, 2023
Rocco P.
europepmc   +1 more source

Intravenous iron isomaltoside 1000 administered by high single-dose infusions or standard medical care for the treatment of fatigue in women after postpartum haemorrhage: study protocol for a randomised controlled trial [PDF]

, 2015
Charlotte Holm, Lars Lykke Thomsen, Astrid Nørgaard, Jens Langhoff‐Roos   +3 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Sleep, Hormones, and Circadian Rhythms throughout the Menstrual Cycle in Healthy Women and Women with Premenstrual Dysphoric Disorder

International Journal of Endocrinology, 2010
Ari Shechter, Diane B. Boivin
doaj   +1 more source

Insufficient weight loss after bariatric surgery and its predictors: Tehran Obesity Treatment Study (TOTS). [PDF]

Langenbecks Arch Surg
Almasi MH, Barzin M, Mahdavi M, Khalaj A, Ebrahimi D, Valizadeh M, Hosseinpanah F.   +6 more
europepmc   +1 more source

Refractive Growth of the Crystalline Lens in the Infant Aphakia Treatment Study. [PDF]

Ophthalmol Sci, 2022
McClatchey TS, Lambert SR, Morrison DG, Kruger SJ, Wilson LB, McClatchey SK, Infant Aphakia Treatment Study Group.   +6 more
europepmc   +1 more source

Pregnancy Outcomes after Treatment for Cervical Cancer Precursor Lesions: An Observational Study

, 2017
Sheila Weinmann, Allison L. Naleway, Geeta K. Swamy, Girishanthy Krishnarajah, Bhakti Arondekar, Jovelle Fernandez, Evan R. Myers   +6 more
openalex   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Steerable versus Conventional flexible and navigable suction ureteral access sheath (FANS) flexible Ureteroscopy for Lower Pole stones Treatment: study protocol for a multicentre, randomised superiority trial (SCULPT trial). [PDF]

BMJ Open
Yuen SKK, Liu S, Gauhar V, Mai H, He W, Hu H, Ke C, Dai Y, Shan L, Jiang Y, Yuan J, Cao Z, Zuo L, Yang C, Bai B, Bi X, Zhao H, Xi M, Ding N, Deng S, Tang S, Zeng J, Du J, Wu W, Ma J, Zhong W, Zhao Z, Liu Y, de la Rosette J, Zeng G, Zhu W.   +30 more
europepmc   +1 more source