Results 181 to 190 of about 2,310,445 (232)

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

Advanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang, Tong Wan, Siyue Zhang, Yunzhen Jiang, Peng Su, Jixin Liu, Zhitong Chen, Jie Hao, Haoyu Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Tao Xing, Qihuang Zhang, Ulf Schmitz, Zhiyong Ding, Nicola Crosetto, Bingqiang Liu, Qifeng Yang   +18 more
wiley   +1 more source

Dynamic stability of climate-growth relationships in <i>Picea crassifolia</i> in the Qilian Mountains: the modulating role of elevation gradient and time-varying characteristics. [PDF]

Front Plant Sci
Zhao J, Gao Y, Wu X, Ren X, Ma X, Yuan H, Zhao W, Zhao N, Vrahnakis M, Kastridis A, Wei N, Jing W.   +11 more
europepmc   +1 more source

Sandwich‐Structured Aramid Composite Papers with Heterogeneous Dielectric Layers for Integrated Corona Resistance and Thermal Conductivity

Advanced Science, EarlyView.
A sandwich‐structured aramid composite paper was designed to integrate high corona resistance and thermal conductivity. The fluorinated graphene/aramid surface layers effectively dissipate space charges to suppress corona discharge. Meanwhile, the boron nitride nanotube/aramid core layer constructs continuous heat‐conduction pathways.
Jun‐Wen Ren, Jun‐Xue Chen, Ying‐Ying Tong, Zi Wang, Jia‐Cheng Zhang, Lin Zhang, Bo Zhang, Fan Zhang, Guo‐Long Wang, Jun‐Wei Zha, Shen‐Li Jia   +10 more
wiley   +1 more source

A new species of <i>Serpinema</i> Yeh (1960) (Nematoda: Camallanidae) in a captive false map turtle, <i>Graptemys pseudogeographica pseudogeographica</i> (Gray, 1831) (Testudines: Emydidae), in Portugal. [PDF]

Int J Parasitol Parasites Wildl
Cruz JT, Cruz A, Carvalho V, Maia C, Parreira R, Ramilo DW, Pereira A.   +6 more
europepmc   +1 more source

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

Divergent climate-growth responses in radial growth of Chinese pine forests with varying health conditions in the semi-arid Loess Plateau, China. [PDF]

Front Plant Sci
Hongyi L, Xuchun L, Haixia Y, Qindi Z, Zongshan L.   +4 more
europepmc   +1 more source

Disentangling Heterogeneous Molecular Networks for Multi‐Omics‐Driven Cancer Driver Discovery

Advanced Science, EarlyView.
DRIVE integrates PPI topology and pan‐cancer multi‐omics profiles through dual‐view graph disentanglement, contrastive representation learning, and joint optimization. Across six PPI networks, DRIVE outperforms ten baselines and remains robust to structural and annotation perturbations.
Xinjing Gong, Ji Li, Mu Su, Peishen Yu, Te Ma, Ruiyang Zhai, Chenye Zhang, Mengyan Zhang, Yan Zhang   +8 more
wiley   +1 more source

Tree-ring stable isotopes and growth trajectories reveal early warning signals of drought-induced Scots pine mortality. [PDF]

Tree Physiol
Urban O, Hartl C, Zang C, Pernicová N, Čáslavský J, Treydte K, Schneider L, Trnka M, Esper J, Büntgen U.   +9 more
europepmc   +1 more source

Bio‐Inspired Gradient Heterogeneous Architectures for Ultrasensitive and Robust Strain Sensors via Programmable Crack Engineering

Advanced Science, EarlyView.
Inspired by the insect campaniform sensillum, a heterogeneous bilayer strain sensor is developed based on a unique impedance mismatch and three‐dimensional structural dynamic percolation strategy. The sensor enables real‐time multi‐joint teleoperation of three joints and the gripper using a six‐degree‐of‐freedom robotic‐arm platform.
Qi Wu, Tiantong Wang, Yinhao Wang, Yanggang Feng, Yan Huang   +4 more
wiley   +1 more source