Results 21 to 30 of about 50,482 (252)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Drought Sensitivity of Slash Pine and Longleaf Pine Deduced by Tree Ring Analysis [PDF]

, 2014
Annual tree rings give us the opportunity to investigate the adaptation of trees to climate and environmental changes over a long period of time. In particular, the physical characteristics of each ring (width and earlywood and late wood differentiation)
Madison, Conor
core   +1 more source

The reconstructed Indonesian warm pool sea surface temperatures from tree rings and corals: Linkages to Asian monsoon drought and El Niño–Southern Oscillation [PDF]

, 2006
[ 1] The west Pacific warm pool is the heat engine for the globe's climate system. Its vast moisture and heat exchange profoundly impact conditions in the tropics and higher latitudes.
Aldrian, Alexander Tudhope, Allan, Ashley Curtis, Barlow, Chang, Charles, Charles, Chenoweth, Cobb, Cobb, Cole, Cook, Cook, Cook, Cook, Cook, Cook, D'Arrigo, D'Arrigo, D'Arrigo, D'Arrigo, Dai, Dai, Dawdy, Deser, Emanuel, Esper, Evans, Evans, Fox, Fritts, Fritts, Graham, Grove, Harger, Hoerling, Holmes, John Sakulich, Jonathan Palmer, Kaplan, La Ode Ngkoimani, Linsley, Linsley, Lough, Mann, Mann, Mantua, Meko, Ortlieb, Paul Krusic, Quinn, Rob Wilson, Rosanne D'Arrigo, Satria Bijaksana, Schneider, Simkin, Siti Zulaikah, Sontakke, Stahle, Sun, Tourre, Tudhope, von Storch, Wang, Wilson   +65 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Moisture increase in response to high-altitude warming evidenced by tree-rings on the southeastern Tibetan Plateau [PDF]

, 2017
Rapid warming has been observed in the high-altitude areas around the globe, but the implications on moisture change are not fully understood. Here we use tree-rings to reveal common moisture change on the southeastern Tibetan Plateau (TP) during the ...
Fang, K, Li, J, Pak, HY, Shi, J, Yang, B, Zhang, DD   +5 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

IntCal09 and Marine09 radiocarbon age calibration curves, 0-50,000yeats cal BP [PDF]

, 2009
The IntCal04 and Marine04 radiocarbon calibration curves have been updated from 12 cal kBP (cal kBP is here defined as thousands of calibrated years before AD 1950), and extended to 50 cal kBP, utilizing newly available data sets that meet the IntCal ...
Bard, Edouard, Bayliss, Alex, Beck, J. Warren, Blackwell, Paul G., Bronk Ramsey, Christopher, Buck, Caitlin E., Cheng, Hai, Edwards, R. Lawrence, Friedrich, Michael, Grootes, Pieter M., Guilderson, Thomas P., Haflidason, Haflidi, Hajdas, Irka, Hatte, Christine, Heaton, Timothy J., Hoffmann, Dirk L., Hogg, Alan G., Hughen, Konrad A., Kaiser, K. Felix, Kromer, Bernd, Manning, Sturt W., Niu, Mu, Reimer, Paula J., Reimer, Ron W., Richards, David A., Scott, E. Marian, Southon, John R., Staff, Richard A., Turney, Christian S. M., van der Plicht, Johannes   +29 more
core   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

DendroSync: An R package to unravel synchrony patterns in tree-ring networks [PDF]

, 2017
Spatial synchrony refers to the presence of a common signal for a time-varying characteristic that, in dendrosciences, is shared among tree-ring chronologies from a particular area.
Alday, Josu G., Resco de Dios, Víctor, Shestakova, Tatiana A., Voltas Velasco, Jordi   +3 more
core   +2 more sources