Results 51 to 60 of about 1,368,146 (280)
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Cyclic Variation of Residual (CO2 + H2O) and Total Pressure in Conifer Stem and Woody Root Tree Rings [PDF]
Tree-ring chronologies of stem discs and core samples have been widely used to reconstruct the climatic conditions of tree growth. However, insufficient attention has been given to the fact that root and stem wood accumulate biogenic gases, whose ...
Boris G. Ageev +2 more
doaj
The use of X-ray method to study annual growth variation of Pinus eldarica [PDF]
Using non-destructive methods to study forest productivity and wood quality as well as annual growth variations deserve special importance. In this regard annual growth changes of Pinus eldarica include width of the spring and summer rings and percentage
Saeid Mehrabi
doaj +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Free trace metals are one of the most relevant environmental problems of today; consequently, it is becoming important to evaluate their spatial distribution and accumulation rates in the natural environment.
Pranas Baltrėnas, Dovilė Vaitkutė
doaj +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Extracting a common high frequency signal from Northern Quebec black spruce tree-rings with a Bayesian hierarchical model [PDF]
One basic premise of dendroclimatology is that tree rings can be viewed as climate proxies, i.e. rings are assumed to contain some hidden information about past climate.
J.-J. Boreux +4 more
doaj

