Results 91 to 100 of about 5,537,193 (382)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

On Trees with a Given Number of Vertices of Fixed Degree and Their Two Bond Incident Degree Indices

Axioms
This paper is mainly concerned with the study of two bond incident degree (BID) indices, namely the variable sum exdeg index SEIa and the general zeroth-order Randić index Rα0.
Abeer M. Albalahi, Muhammad Rizwan, Akhlaq A. Bhatti, Ivan Gutman, Akbar Ali, Tariq Alraqad, Hicham Saber   +6 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Entrebanquets [PDF]

, 1993
Localització: Universitat Autònoma de Barcelona, Arb 491.Forma part del fons personal de Jordi Arbonès.Text ...
Tree, Matthew.
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Auto-Configuration of ACL Policy in Case of Topology Change in Hybrid SDN

IEEE Access, 2016
Software-defined networking (SDN) has emerged as a new network architecture, which decouples both the control and management planes from data plane at forwarding devices.
Rashid Amin, Nadir Shah, Babar Shah, Omar Alfandi   +3 more
doaj   +1 more source

The role of anthropogenic dispersal in shaping the distribution and genetic composition of a widespread North American tree species [PDF]

, 2021
Graham E. Wyatt, J. L. Hamrick, Dorset W. Trapnell   +2 more
openalex   +1 more source

An FPT 2-Approximation for Tree-Cut Decomposition

, 2015
The tree-cut width of a graph is a graph parameter defined by Wollan [J. Comb. Theory, Ser. B, 110:47-66, 2015] with the help of tree-cut decompositions.
B Courcelle, DM Thilikos, DM Thilikos, HL Bodlaender, HL Bodlaender, HL Bodlaender, M Dom, MR Fellows, MR Garey, N Robertson, N Robertson, N Robertson, P Wollan, PA Golovach, PD Seymour, PD Seymour, R Ganian, T Kloks   +17 more
core   +1 more source

The Tree of Knowledge: The Biological Roots of Human Understanding

, 2007
A review of The Tree of Knowledge: The Biological Roots of Human Understanding, by Humberto R. Maturana and Francisco J. Varela, 1998 [1987]. Revised Edition. Boston and London: Shambhala Publications, 269 pp. ISBN 0877736421. $29.95 USD.
Yves Laberge
semanticscholar   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source