Results 101 to 110 of about 264,426 (285)

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Distribution of Frost Damages in Siberian Spruce (Picea Obovata Ledeb.) on the Two Different Slope Aspects at the Upper Tree Line Ecotone of the Southern Urals [PDF]

open access: yesЖурнал Сибирского федерального университета: Серия Биология, 2011
The analysis of extreme weather events provides an opportunity to study the microclimate characteristics on different slope aspects of the mountains. About 540 samples of wood of Siberian spruce (Picea obovata Ledeb.) on the north-eastern faced slope and
Marina A. Gurskaya, Pavel A. Moiseev
doaj  

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon   +10 more
wiley   +1 more source

Splitting trees stopped when the first clock rings and Vervaat's transformation

open access: yes, 2011
We consider a branching population where individuals have i.i.d.\ life lengths (not necessarily exponential) and constant birth rate. We let $N_t$ denote the population size at time $t$. %(called homogeneous, binary Crump--Mode--Jagers process).
Lambert, Amaury, Trapman, Pieter
core  

Multiscale Structuring of Hydroxyapatite via Two‐Photon Lithography of Nanocomposites

open access: yesAdvanced Functional Materials, EarlyView.
Hydroxyapatite scaffolds are of great interest in bone tissue engineering applications, ranging from 3D cell culture to regenerative medicine. Using two‐photon lithography of a transparent nanocomposite, hydroxyapatite microstructures with features ranging from submicron to centimeter‐scale are fabricated. This allows to mimic the natural bone geometry,
Leonhard Hambitzer   +6 more
wiley   +1 more source

The Effect of Purcell Cavities on the Lifetime of Thermally Activated Delayed Fluorescent Emitters

open access: yesAdvanced Functional Materials, EarlyView.
A pressing challenge to OLED displays and lighting is to balance high efficiency and long operational lifetime in the deep blue spectrum. The Purcell effect can reduce the triplet density and hence the probability for destructive energy‐driven triplet annihilation events that limit the OLED lifetime. Here we study of the Purcell effect on two different
Sritoma Paul   +4 more
wiley   +1 more source

Tree growth and vegetation activity at the ecosystem-scale in the eastern Mediterranean

open access: yesEnvironmental Research Letters, 2017
Linking annual tree growth with remotely-sensed terrestrial vegetation indices provides a basis for using tree rings as proxies for ecosystem primary productivity over large spatial and long temporal scales.
Bethany L Coulthard   +4 more
doaj   +1 more source

Circular‐Polarization‐Sensitive Organic Photodetectors with a Chiral Nanopatterned Electrode Inverse‐Designed by Genetic Algorithm

open access: yesAdvanced Functional Materials, EarlyView.
A chiral photodetector capable of selectively distinguishing left‐ and right‐handed circularly polarized light is experimentally demonstrated. The device, which features a nanopatterned electrode inverse‐designed by a genetic algorithm within a metal–dielectric–metal nanocavity that incorporates a vacuum‐deposited small‐molecule multilayer, exhibits ...
Kyung Ryoul Park   +3 more
wiley   +1 more source

Single‐Crystalline Lateral p‐SnS/n‐SnSe van der Waals Heterostructures by Vapor Transport Growth with In Situ Bi Doping

open access: yesAdvanced Functional Materials, EarlyView.
In‐situ doping during growth of SnSe and subsequent attachment of SnS produces high‐quality lateral pn‐heterojunctions between van der Waals semiconductors. Electron beam induced current measurements demonstrate electrically active pn‐junctions, paving the way for devices that harness charge separation at lateral interfaces in layered heterostructures.
Peter Sutter   +4 more
wiley   +1 more source

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