Results 191 to 200 of about 919,373 (313)

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

open access: yesAdvanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang   +7 more
wiley   +1 more source

Generalized centrality in trees

open access: yes
In 1982, Slater defined path subgraph analogues to the center, median, and (branch or branchweight) centroid of a tree. We define three families of central substructures of trees, including three types of central subtrees of degree at most D that yield ...
Pelsmajer, M.J.   +2 more
core  

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

open access: yesAdvanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma   +11 more
wiley   +1 more source

Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)

open access: yesAdvanced Science, EarlyView.
ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang   +14 more
wiley   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

open access: yesAdvanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang   +7 more
wiley   +1 more source

An Integrated NLP‐ML Framework for Property Prediction and Design of Steels

open access: yesAdvanced Science, EarlyView.
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju   +5 more
wiley   +1 more source

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