Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
The role of stem respiration in cold-acclimation of winter-dormant Quercus robur trees under large air temperature fluctuations. [PDF]
Rodríguez-Calcerrada J +3 more
europepmc +1 more source
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Growth patterns and climate sensitivity differ for understory and canopy trees. [PDF]
Kašpar J +5 more
europepmc +1 more source
An Integrated NLP‐ML Framework for Property Prediction and Design of Steels
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju +5 more
wiley +1 more source
Population history rather than tree age contributes to the evolutionary importance of ancient trees in an endangered conifer. [PDF]
Zhang WP +5 more
europepmc +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
Urban-suburban differences in the response of typical greening tree species to extreme drought in a subtropical city. [PDF]
Lei Y +5 more
europepmc +1 more source
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li +14 more
wiley +1 more source
Questioning the evidence for host-symbiont codiversification in mycorrhizal symbioses. [PDF]
Bodin F, Morlon H, Perez-Lamarque B.
europepmc +1 more source

