Results 241 to 250 of about 4,210,592 (370)

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

Advanced Theory and Simulations, EarlyView.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer, Sridhar Priyankha, Gopal Hema, Anouar Zerouali, Hamza Haddag, Muneerah Mogren Al Mogren, Muthuramalingam Prakash, Majdi Hochlaf   +7 more
wiley   +1 more source

Exotic ambrosia beetles and phytopathogenic fungi associated with rapid apple decline in North Carolina. [PDF]

J Econ Entomol
Gresham SDM, Ranger CM, Walgenbach JF, Villani SM.   +3 more
europepmc   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

A Squirrel's Guide to the Olive Galaxy: Tree-Level Determinants of Den-Site Selection in the Persian Squirrel within Traditional Mediterranean Olive Groves. [PDF]

Biology (Basel)
Zevgolis YG, Kamatsos E, Christopoulos A, Valeta C, Rekouti E, Xagoraris C, Mitsainas GP, Lymberakis P, Youlatos D, Dimitrakopoulos PG.   +9 more
europepmc   +1 more source

Probability on Trees and Networks

, 2017
R. Lyons, Y. Peres
semanticscholar   +1 more source

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

Advanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu, Wenqiang Wan, Qingquan Liang, Hengsong Yang, Chengcong Lu, Taiyun Wei, Qian Chen   +6 more
wiley   +1 more source

<i>Harungana madagascariensis</i> (Hypericaceae) is a key phorophyte for native epiphytes and lianas during ecological restoration: case study on an oceanic island. [PDF]

PeerJ
Baguette FMMP, Baider C, Florens FBV.
europepmc   +1 more source

Multiplicative Tree-Structured Long Short-Term Memory Networks for Semantic Representations [PDF]

, 2018
Nam Khanh Tran, Weiwei Cheng
openalex   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Assessment of Landslide Activity and Hazard Recorded in Tree Rings-Examples from the High-Risk Vernazza Catchment (Liguria, Italy). [PDF]

Sensors (Basel)
Malik I, Maerker M, Wistuba M, Gorczyca E, Torrese P, Niyokwiringirwa P, Yu Y, Woskowicz-Ślęzak B, Bieniasz A.   +8 more
europepmc   +1 more source