Results 301 to 310 of about 2,687,568 (346)
Chronic disturbance alters seed dispersal traits and frugivores resources in a dry tropical forest. [PDF]
Espinosa CI+7 more
europepmc +1 more source
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang+12 more
wiley +1 more source
Computational intelligence modeling and optimization of small molecule API solubility in supercritical solvent for production of drug nanoparticles. [PDF]
Liang J, Zhao H, Zhou S, Gao Y.
europepmc +1 more source
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan+11 more
wiley +1 more source
Uniform regulation of stomatal closure across temperate tree species to sustain nocturnal turgor and growth. [PDF]
Peters RL+8 more
europepmc +1 more source
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang+13 more
wiley +1 more source
Ecosystem benefits of urban woody plants for sustainable green space planning: a case study from Wroclaw. [PDF]
Strashok O, Bidolakh D, Ziemiańska M.
europepmc +1 more source
This study investigates bidirectional introgression between Chinese and European pig populations, revealing 3558 introgressed genomic segments and 30 structural variations. Analysis of the BMP2 region suggests its role in body size enhancement. By integrating ancient and modern genomes, the study highlights the impact of introgression on genetic ...
Yibin Qiu+19 more
wiley +1 more source