Results 41 to 50 of about 844,604 (299)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Transcriptome Analysis of the Late-Acting Self-Incompatibility Associated with RNase T2 Family in Camellia oleifera

Plants, 2023
The Camellia oil tree (Camellia oleifera Abel.) is an important nonwood forest species in China, and the majority of its cultivars are late-acting self-incompatibility (LSI) types.
Chang Li, Mengqi Lu, Junqin Zhou, Sen Wang, Yi Long, Yan Xu, Xiaofeng Tan   +6 more
doaj   +1 more source

Iteration Trees [PDF]

Journal of the American Mathematical Society, 1994
This paper gives a further report on work done some years ago, which has led to relatively complete understanding of the relationship between the consistency of determinacy and large cardinals.
Martin, D. A., Steel, J. R.
openaire   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Transcriptomic and metabolomic profiling provide novel insights into fruit development and flesh coloration in Prunus mira Koehne, a special wild peach species

BMC Plant Biology, 2019
Background Flesh color is one of the most important traits for the commercial value of peach fruit. To unravel the underlying regulatory network in Prunus mira, we performed an integrated analysis of the transcriptome and metabolome of 3 fruit types with
Hong Ying, Jian Shi, Shanshan Zhang, Gesang Pingcuo, Shuo Wang, Fan Zhao, Yongning Cui, Xiuli Zeng   +7 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Analysis of combining ability and heterosis based on controlled pollination populations of eucalypt

Scientific Reports
Artificial hybridization remains the most effective method for genetic improvement of eucalypt, though limited research exists on the genetic basis of heterosis for interesting traits in Chinese eucalypt.
Zhiyi Su, Wanhong Lu, Haoyang Cao, Guo Liu, Yan Lin, Anying Huang, Jianzhong Luo   +6 more
doaj   +1 more source

Tree 2 – Decision Trees for Tree Structured Data [PDF]

, 2005
We present Tree2, a new approach to structural classification. This integrated approach induces decision trees that test for pattern occurrence in the inner nodes. It combines state-of-the-art tree mining with sophisticated pruning techniques to find the most discriminative pattern in each node. In contrast to existing methods, Tree2 uses no heuristics
Bringmann, Björn, Zimmermann, Albrecht
openaire   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Population structure, genetic diversity and genome-wide association analysis of the seed morphology traits in Handroanthus chrysanthus (Jacq.) s.o.grose

BMC Plant Biology
Background Handroanthus chrysanthus is a remarkable landscape tree species with significant research and development potential. However, it remains unclear whether the varieties introduced to China are one species or two species.
Xiuhua Shang, Zhihua Wu, Guowu Zhang, Youshuang Wang, Xiaoming Li, Peijian Zhang   +5 more
doaj   +1 more source