Results 111 to 120 of about 1,723,261 (194)
Diagnosis and Management of Nitazene Dependence in Sydney, Australia: A Case Series
ABSTRACT Introduction Nitazenes are synthetic opioids with potent μ‐receptor activity. There are increasing reports of nitazene overdoses worldwide. We report on a case series of protonitazene and metonitazene dependence responding to high dose medication for the treatment of opioid dependence in both inpatient and outpatient settings.
Daniel Dutkiewicz +6 more
wiley +1 more source
Abstract On 2 May 2025, an Mw 7.4 earthquake occurred ∼120 km off the southern tip of Tierra del Fuego, at the transition of the Shackleton Fracture Zone and the Chile Trench. This event exhibits reverse‐faulting mechanisms with relatively steeply dipping planes and is the largest recorded along this complex plate boundary.
A. Vuan +11 more
wiley +1 more source
Patch Interactions on a Heterogeneous Fault Drive Nearby Slow and Fast Earthquakes
Abstract Tectonic tremor and repeating/regular earthquakes off Iwate in the shallow Japan Trench occur episodically and in spatially overlapping areas, implying a common aseismic driver. We investigate how small aseismic slip triggers events across multiple slip‐rate regimes using fully dynamic earthquake‐cycle simulations governed by rate‐and‐state ...
Yuki Watanabe, Yuta Mitsui
wiley +1 more source
The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London [PDF]
Zapata GP. The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London. COMCAD Arbeitspapiere - Working Papers, 106.
Zapata, Gisela P.
core
Abstract Earthquakes affect surrounding fault systems through multiple mechanisms. Here, we examine a rare cessation of activity in 27 families of low‐frequency earthquakes (LFEs) that likely reflect fault creep at the southern edge of Cascadia subduction, near the Mendocino triple junction.
David R. Shelly, Kathryn Z. Materna
wiley +1 more source
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie +12 more
wiley +1 more source
Pharmacotherapy of Essential Tremor
Essential tremor (ET) is a common movement disorder but its pathogenesis remains poorly understood. This has limited the development of effective pharmacotherapy.
František Cibulcík +2 more
core +1 more source
The ethanolic leaf extract of Mouriri elliptica exhibited antibacterial and antibiofilm activities against multidrug‐resistant clinical isolates and enhanced the activity of ampicillin. Its diverse chemical profile and low acute toxicity support this Cerrado species as a promising source of natural antibacterial adjuvants. ABSTRACT Bacterial resistance
Talita Vilalva Freire +9 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Movement Disorders in Developmental and Epileptic Encephalopathies
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad +2 more
wiley +1 more source

