Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery +25 more
wiley +1 more source
Investigation of neglected bacterial pathogens provides molecular and serological evidence of Bartonella spp. in patients with acute undifferentiated febrile illness in Villeta, Colombia. [PDF]
Silva-Ramos CR +10 more
europepmc +1 more source
Acute Rickettsiosis Triggering <i>Plasmodium vivax</i> Relapse in a Returned Traveler: A Case Report and Clinical Review of Travel-Related Coinfections. [PDF]
Bagga R +7 more
europepmc +1 more source
ABSTRACT This essay examines the controversy surrounding the Bhoot Vidya certificate program proposed by the Faculty of Ayurveda at Banaras Hindu University in 2019. Drawing on media coverage, curricular materials, and government policy, I analyze how the debate reveals broader tensions in the politics of contemporary Ayurveda, nationalism, and ...
Thomas Seibel
wiley +1 more source
Machine learning reveals drivers of cold-related illness during energy infrastructure attacks in Wartime Ukraine. [PDF]
Marvi K +8 more
europepmc +1 more source
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Coexistence of cat scratch disease lymphadenitis and active pulmonary tuberculosis in an immunocompetent host - a case report with metagenomic diagnosis and literature review. [PDF]
Wang X, Chen S, Yang C.
europepmc +1 more source
Frayed Rope and Resilient Threads: Fijian Healthcare and the COVID‐19 Pandemic
ABSTRACT In April 2021, Fiji faced international scrutiny due to ‘horrific’ hospital conditions, including staff and patients lacking food, non‐operational operating theatres, and critical shortages of beds, medicine, and equipment. After successfully avoiding a major outbreak in 2020, a sudden surge in COVID‐19 cases in 2021 overwhelmed the public ...
Sharon McLennan +3 more
wiley +1 more source
Neuroretinitis: a comprehensive review on aetiologies, clinical manifestations, and treatment options. [PDF]
Shi J, Danesh-Meyer HV, Bhatti MT.
europepmc +1 more source

