Results 121 to 130 of about 7,486,166 (326)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Environmental DNA metabarcoding of pan trap water to monitor arthropod‐plant interactions

open access: yesEnvironmental DNA
Globally, the diversity of arthropods and the plants upon which they rely are under increasing pressure due to a combination of biotic and abiotic anthropogenic stressors.
Joshua H. Kestel   +5 more
doaj   +1 more source

Empirical Study of the 1-2-3 Trend Indicator [PDF]

open access: yes, 2013
In this paper we study automatically recognized trends and investigate their statistics. To do that we introduce the notion of a wavelength for time series via cross correlation and use this wavelength to calibrate the 1-2-3 trend indicator of Maier ...
Hafizogullari, Yasemin   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Organically Produced Foods - A Competitive Approach for the Twenty-First Century in Terms of Blue Ocean New Strategic Concept [PDF]

open access: yesRevista de Management Comparat International, 2011
The Blue Ocean Strategy provides a systematic approach to transform the competition in a less significant factor. This new concept provides companies and entrepreneurs ways to circumvent the fierce competition in the markets where there is a growing ...
George PLESOIANU   +1 more
doaj  

Computational Study of Halide Perovskite-Derived A$_2$BX$_6$ Inorganic Compounds: Chemical Trends in Electronic Structure and Structural Stability [PDF]

open access: green, 2017
Yao Cai   +9 more
openalex   +1 more source

Trend Inflation, Taylor Principle and Indeterminacy [PDF]

open access: yes
Even low levels of trend inflation substantially affect the dynamics of a basic new Keynesian DSGE model when monetary policy is conducted by a contemporaneous Taylor rule. Positive trend inflation shrinks the determinacy region.
Guido Ascari, Tiziano Ropele
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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