Results 161 to 170 of about 5,983,003 (293)
The Impact of Improved Population Life Expectancy in Survival Trend Analyses of Specific Diseases. [PDF]
Health Serv Res, 2016 van Walraven C.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Child undernutrition in Kenya: trend analyses from 1993 to 2008-09. [PDF]
BMC Pediatr, 2014 Matanda DJ, Mittelmark MB, Kigaru DM.
europepmc +1 more source
Metagenomic Analyses: Past and Future Trends
, 2018 Metagenomics has revolutionized microbiology by paving the way for a cultivation-independent assessment and exploitation of microbial communities present in complex ecosystems. Metagenomics comprising construction and screening of metagenomic DNA libraries has proven to be a powerful tool to isolate new enzymes and drugs of industrial importance.
Simon, Carola, Daniel, Rolf
openaire +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Trend analyses of insulin delivery systems in the United States. [PDF]
J Diabetes Sci Technol, 2011 Lee LJ, Li Q, Reynolds MW, Engelman W.
europepmc +1 more source
The trend growth rate of employment : past, present, and future [PDF]
Over the course of the recovery from the 2001 recession, many forecasters have revised downward their expectations for job growth in the United States. The often disappointing pace of employment growth has been attributed to various forces, such as the ...
Todd E. Clark, Taisuke Nakata
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Multilevel and spatial-time trend analyses of the prevalence of hypertension in a large urban city in the USA. [PDF]
J Urban Health, 2013 Liu L +5 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source